Publications 2012
2012
Scientific Journals:
- J. Speck, J. Hecky, H.-K. Tam, K. M. Arndt, O. Einsle, K. M. Mueller: Exploring the Molecular Linkage of Protein Stability Traits for Enzyme Optimization by Iterative Truncation and Evolution. Biochemistry, 2012; 51 (24): 4850-4867.
- C. Fatouros, G.J. Pir, J. Biernat, S.P. Koushika, E. Mandelkow, E.M. Mandelkow, E. Schmidt, R. Baumeister: Inhibition of Tau aggregation in a novel C. elegans model of Tauopathy mitigates proteotoxicity. Hum Mol Genet, 2012. http://dx.doi.org/10.1093/hmg/dds190
- P. Dalle Pezze, A.G. Sonntag, A. Thien, M.T. Prentzell, M. Godel, S. Fischer, E. Neumann-Haefelin, T.B. Huber, R. Baumeister, D.P. Shanley, K. Thedieck: A Dynamic Network Model of mTOR Signaling Reveals TSC-Independent mTORC2 Regulation. Sci Signal, 2012; 5 (217): ra25. http://dx.doi.org/10.1126/scisignal.2002469
- S. Liu, E. Schulze, R. Baumeister: Temperature- and Touch-Sensitive Neurons Couple CNG and TRPV Channel Activities to Control Heat Avoidance in Caenorhabditis elegans. Plos One, 2012; 7 (3): e32360. http://dx.doi.org/10.1371/journal.pone.0032360
- W. Qi, X. Huang, E. Neumann-Haefelin, E. Schulze, R. Baumeister: Cell-Nonautonomous Signaling of FOXO/DAF-16 to the Stem Cells of Caenorhabditis elegans. PLOS Genetics, 2012; 8: e1002836.
- A. Sesarman, E. Oswald, M.T. Chiriac, K. Csorba, V. Vuta, V. Feldrihan, A. Baican, L. Bruckner-Tuderman, C. Sitaru: Why human pemphigoid autoantibodies do not trigger disease by the passive transfer into mice? Immunol Lett, 2012; http://dx.doi.org/10.1016/j.imlet.2012.01.006
- A.W. Arnold, D. Kiritsi, R. Happle, J. Kohlhase, I. Hausser, L. Bruckner-Tuderman, C. Has, P.H. Itin: Type 1 Segmental Galli-Galli Disease Resulting from a Previously Unreported Keratin 5 Mutation. J Invest Dermatol, 2012; http://dx.doi.org/10.1038/jid.2012.72
- C. Has, G. Sparta, D. Kiritsi, L. Weibel, A. Moeller, V. Vega-Warner, A. Waters, Y. He, Y. Anikster, P. Esser, B.K. Straub, I. Hausser, D. Bockenhauer, B. Dekel, F. Hildebrandt, L. Bruckner-Tuderman, G.F. Laube: Integrin alpha3 mutations with kidney, lung, and skin disease. New Engl J Med, 2012; 366 (16): 1508-1514. http://dx.doi.org/10.1056/NEJMoa1110813
- C.W. Franzke, C. Cobzaru, A. Triantafyllopoulou, S. Loffek, K. Horiuchi, D.W. Threadgill, T. Kurz, N. van Rooijen, L. Bruckner-Tuderman, C.P.Blobel: Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation. J Exp Med, 2012. http://dx.doi.org/10.1084/jem.20112258
- D. Kiritsi, M. Pigors, I. Tantcheva-Poor, C. Wessel, M.J. Arin, J. Kohlhase, L. Bruckner-Tuderman, C. Has: Epidermolysis Bullosa Simplex Ogna Revisited. J Invest Dermatol, 2012; doi:10.1038/jid.2012.248
- D. Kiritsi, Y. He, A. M.G. Pasmooij, M. Onder, R. Happle, M. Jonkman, L. Bruckner-Tuderman, C. Has: Revertant mosaicism in a human skin fragility disorder results from slipped mispairing and mitotic recombination. J Clin Invest. 2012; 122(5): 1742–1746. doi:10.1172/JCI61976
- D.T. Behrens, D. Villone, M. Koch, G. Brunner, L. Sorokin, H. Robenek,L. Bruckner-Tuderman, P. Bruckner, U. Hansen: The epidermal basement membrane is a composite of separate laminin- or collagen IV-containing networks connected by aggregated perlecan, but not by nidogens. J Biol Chem, 2012; http://dx.doi.org/10.1074/jbc.M111.336073
- E. Oswald, A. Sesarman, C.W. Franzke, U. Wolfle, L. Bruckner-Tuderman, T. Jakob, S.F. Martin, C. Sitaru: The flavonoid luteolin inhibits fcgamma-dependent respiratory burst in granulocytes, but not skin blistering in a new model of pemphigoid in adult mice. Plos One, 2012; 7 (2): e31066. http://dx.doi.org/10.1371/journal.pone.0031066
- M. Pigors, D. Kiritsi, C. Cobzaru, A. Schwieger-Briel, J. Suarez, F. Faletra, H. Aho, L. Makela, J.S. Kern, L. Bruckner-Tuderman, C. Has: TGM5 Mutations Impact Epidermal Differentiation in Acral Peeling Skin Syndrome. J Invest Dermatol, 2012. http://dx.doi.org/10.1038/jid.2012.166
- S. Loffek, L. Bruckner-Tuderman, T.M. Magin: Involvement of the ubiquitin-proteasome system in the stabilization of cell-cell contacts in human keratinocytes. Exp Dermato, 2012. http://dx.doi.org/10.1111/j.1600-0625.2012.01564.x
- T. Hurskainen, J. Moilanen, R. Sormunen, C.W. Franzke, R. Soininen, S. Loeffek, L. Huilaja, M. Nuutinen, L. Bruckner-Tuderman, H. Autio-Harmainen, K. Tasanen: Transmembrane collagen XVII is a novel component of the glomerular filtration barrier. Cell Tissue Res, 2012; http://dx.doi.org/10.1007/s00441-012-1368-x
- W. Nishie, J. Jackow, S.C. Hofmann, C.W. Franzke, L. Bruckner-Tuderman: Coiled-coils ensure the physiological ectodomain shedding of collagen XVII. J Biol Chem, 2012. http://dx.doi.org/10.1074/jbc.M112.345454
- A. Singh, J.M. Nascimento, S. Kowar, H. Busch, M. Börries: Boolean approach to signalling pathway modelling in HGF-induced keratinocyte migration. Bioinformatics, 2012; 28 (18); i495-i501. http://dx.doi.org/10.1093/bioinformatics/bts410
- V. Kuettner, C. Mack, K. Rigbolt, O. Schilling, H. Busch, L. Bruckner-Tuderman, J. Dengjel: Disease proteomics reveals modulation of cell microenvironment in recessive dystrophic epidermolysis bullosa. Journal of Investigative Dermatology, 2012; 132: S45.
- A. Matheu, M. Collado, C. Wise, L. Manterola, L. Cekaite, A.J. Tye, M. Canamero, L. Bujanda, A. Schedl, K.S. Cheah, R.I. Skotheim, R.A. Lothe, A. Lopez de Munain, J. Briscoe, M. Serrano, R. Lovell-Badge: Oncogenicity of the developmental transcription factor Sox9. Cancer Res, 2012; 72 (5): 1301-1315. http://dx.doi.org/10.1158/0008-5472.CAN-11-3660
- I. Grskovic, A. Kutsch, C. Frie, G. Groma, J. Stermann, U. Schlotzer-Schrehardt, A. Niehoff, S.E. Moss, S. Rosenbaum, E. Poschl, M. Chmielewski, G. Rappl, H. Abken, J.F. Bateman, K.S. Cheah, M. Paulsson, B. Brachvogel: Depletion of annexin A5, annexin A6 and collagen X causes no gross changes in matrix vesicle mediated mineralization, but lack of collagen X affects hematopoiesis and the Th1/Th2 response. J Bone Miner Res, 2012. http://dx.doi.org/10.1002/jbmr.1682
- Q. Yuan, H. Su, J. Guo, K.Y. Tsang, K.S. Cheah, K. Chiu, J. Yang, W.M. Wong, K.F. So, J.D. Huang, W. Wu, Z.X. Lin: Decreased c-Jun expression correlates with impaired spinal motoneuron regeneration in aged mice following sciatic nerve crush. Exp Gerontol, 2012; 47 (4): 329-336. http://dx.doi.org/10.1016/j.exger.2012.02.006
- Y.H. Fan, y.Q. Song, D. Chan, Y. Takahashi, S. Ikegawa, M. Matsumoto, I. Kou, K.S. Cheah, P. Sham, K.M. Cheung, K.D. Luk: SNP rs11190870 near LBX1 is associated with adolescent idiopathic scoliosis in southern Chinese. J Hum Genet, 2012; 57 (4): 244-246. http://dx.doi.org/10.1038/jhg.2012.11
- A.C. Becker, J. Bunkenborg, T. Eisenberg, L.M. Harder, S. Schroeder, F. Madeo, J.S. Andersen, J. Dengjel: Friend or food: Different cues to the autophagosomal proteome. Autophagy, 2012; 8 (6). http://dx.doi.org/10.1021/pr300375d
- A. Schreiber, Y. Yuan, M.C. Huber, R. Thomann, A. Ziegler, H. Coelfen, J. Dengjel, M. Krueger, S.M. Schiller: From Bioconjugation to Self-Assembly in Nanobiotechnology: Quantum Dots Trapped and Stabilized by Toroid Protein Yoctowells. Advanced Engineering Materials, 2012; 14 (6): B344-B350.
- G. Fuellen, J. Dengjel, A. Hoeflich, J. Hoeijmakers, H.A. Kestler, A. Kowald, S. Priebe, D. Rebholz-Schuhmann, B. Schmeck, U. Schmitz, A. Stolzing, J. Suhnel, D. Wuttke, J. Vera: Systems Biology and Bioinformatics in Aging Research: A Workshop Report. Rejuv Res, 2012. http://dx.doi.org/10.1089/rej.2012.1360
- J. Dengjel, M. Zarei, A. Sprenger, C. Gretzmeier: Combinatorial use of ERLIC and SCX chromatography for in-depth phosphoproteome analysis. J Proteome Res, 2012; 8(6).
- J. Dengjel, M. Hoyer-Hansen, M.O. Nielsen, T. Eisenberg, L.M. Harder, S. Schandorff, T. Farkas, T. Kirkegaard, A.C. Becker, S. Schroeder, K. Vanselow, E. Lundberg, M.M. Nielsen, A.R. Kristensen, V. Akimov, J. Bunkenborg, F. Madeo, M. Jaattela, J.S. Andersen: Identification of autophagosome-associated proteins and regulators by quantitative proteomic analysis and genetic screens. Mol Cell Proteomics, 2012; 11(3). http://dx.doi.org/10.1074/mcp.M111.014035
- L Bozzacco, H. Yu, J. Dengjel C. Trumpfheller, H.A. Zebroski, N. Zhang, V. Kuettner, B.M. Ueberheide, H. Deng, B.T. Chait, R.M. Steinman, S. Mojsov, D. Fenyoe:
Strategy for Identifying Dendritic Cell-Processed CD4(+) T Cell Epitopes from the HIV Gag p24 Protein. PLOS ONE, 2012; 7: e41897. - R. Engelke, A.C. Becker, J. Dengjel: The Degradative Inventory of the Cell: Proteomic Insights. Antioxid Redox Sign, 2012; http://dx.doi.org/10.1089/ars.2011.4393
- V.I. Dumit, J. Dengjel: Autophagosomal protein dynamics and influenza virus infection. Front Immunol, 2012; 3: 43. http://dx.doi.org/10.3389/fimmu.2012.00043
- A. Filippi, C. Jainok, W. Driever: Analysis of transcriptional codes for zebrafish dopaminergic neurons reveals essential functions of Arx and Isl1 in prethalamic dopaminergic neuron development.Dev Biol, 2012. http://dx.doi.org/10.1016/j.ydbio.2012.06.010
- A.M. Fernandes, K. Fero, A.B. Arrenberg, S.A. Bergeron, W. Driever, H.A. Burgess: Deep Brain Photoreceptors Control Light-Seeking Behavior in Zebrafish Larvae.Curr Biol, 2012. http://dx.doi.org/10.1016/j.cub.2012.08.016
- J. Schweitzer, H. Loehr, A. Filippi, W. Driever: Dopaminergic and noradrenergic circuit development in zebrafish. Developmental Neurobiology, 2012; 72 (3): 256-268.
- M. Manoli, W. Driever: Fluorescence-Activated Cell Sorting (FACS) of Fluorescently Tagged Cells from Zebrafish Larvae for RNA Isolation. Cold Spring Harb Protoc, 2012; 2012 (8). http://dx.doi.org/10.1101/pdb.prot069633
- O. Ronneberger, K. Liu, M. Rath, D. Ruebeta, T. Mueller, H. Skibbe, B. Drayer, T. Schmidt, A. Filippi, R. Nitschke, T. Brox, H. Burkhardt, W. Driever: ViBE-Z: a framework for 3D virtual colocalization analysis in zebrafish larval brains.Nat Methods, 2012. http://dx.doi.org/10.1038/nmeth.2076
- J.E. Christensen, C. Fenger, S. Issazadeh-Navikas, A. Krug, P. Liljestrom, S. Goriely, S.R. Paludan, B. Finsen, J.P. Christensen, A.R. Thomsen: Differential impact of interferon regulatory factor 7 in the initiation of the type I interferon response in the LCMV infected CNS versus the periphery. J Virol, 2012; http://dx.doi.org/10.1128/JVI.07090-11
- K.L. Lambertsen, K. Biber, B. Finsen: Inflammatory cytokines in experimental and human stroke. J Cerebr Blood F Met, 2012; 32 (9): 1677-1698. http://dx.doi.org/10.1038/jcbfm.2012.88
- M. Bloksgaard, S. Bek, A.B. Marcher, D. Neess, J. Brewer, H.K. Hannibal-Bach, T. Helledie, C. Fenger, M. Due, Z. Berzina, R. Neubert, J. Chemnitz, B. Finsen, A. Clemmensen, J. Wilbertz, H. Saxtorph, J. Knudsen, L. Bagatolli, S. Mandrup: The Acyl CoA Binding Protein is required for Normal Epidermal Barrier Function in Mice. J Lipid Res, 2012; http://dx.doi.org/10.1194/jlr.M029553
- A.B. Schelin, G. Karolyi, A.P. de Moura, N. Booth, C. Grebogi: Are the fractal skeletons the explanation for the narrowing of arteries due to cell trapping in a disturbed blood flow? Comput Biol Med, 2012; 42 (3): 276-281. http://dx.doi.org/10.1016/j.compbiomed.2011.07.002
- D. Kaloriti, A. Tillmann, E. Cook, M. Jacobsen, T. You, M. Lenardon, L. Ames, M. Barahona, K. Chandrasekaran, G. Coghill, D. Goodman, N.A. Gow, C. Grebogi, H.L. Ho, P. Ingram, A. McDonagh, A.P. Moura, W. Pang, M. Puttnam, E. Radmaneshfar, M.C. Romano, D. Silk, J. Stark, M. Stumpf, M. Thiel, T. Thorne, J. Usher, Z. Yin, K. Haynes, A.J. Brown: Combinatorial stresses kill pathogenic Candida species. Med Mycol, 2012; http://dx.doi.org/10.3109/13693786.2012.672770
- L. Sommerlade, M. Thiel, B. Platt, A. Plano, G. Riedel, C. Grebogi, J. Timmer, B. Schelter: Inference of Granger causal time-dependent influences in noisy multivariate time series. J Neurosci Methods, 2012; 203 (1): 173-185. http://dx.doi.org/10.1016/j.jneumeth.2011.08.042
- M.S. Baptista, R.M. Rubinger, E.R. Viana, J.C. Sartorelli, U. Parlitz, C. Grebogi: Mutual information rate and bounds for it. Plos One, 2012; 7 (10): e46745. http://dx.doi.org/10.1371/journal.pone.0046745
- T. You, P. Ingram, M.D. Jacobsen, E. Cook, A. McDonagh, T. Thorne, M.D. Lenardon, A.P. de Moura, M.C. Romano, M. Thiel, M. Stumpf, N.A. Gow, K. Haynes, C. Grebogi, J. Stark, A.J. Brown: A systems biology analysis of long and short-term memories of osmotic stress adaptation in fungi. BMC Res Notes, 2012; 5 (1): 258. http://www.biomedcentral.com/content/pdf/1756-0500-5-258.pdf
- W.X. Wang, X. Ni, Y.C. Lai, C. Grebogi: Optimizing controllability of complex networks by minimum structural perturbations. Phys Rev E, 2012; 85 (2-2): 026115-026115.
- Y. Li, J. Wang, C. Grebogi, M. Foote, F. Liu: A syringe Focused Ultrasound Device for Simultaneous Injection of DNA and Gene Transfer. J Gene Med, 2012; 14 (1): 54-61. http://dx.doi.org/10.1002/jgm.1633
- B. Spittau, K. Krieglstein: Klf10 and Klf11 as mediators of TGF-beta superfamily signaling. Cell and Tissue Research, 2012; 347 (1): 65-72.
- B. Spittau, L. Wullkopf, X. Zhou, J. Rilka, D. Pfeifer, K. Krieglstein: Endogenous transforming growth factor-beta promotes quiescence of primary microglia in vitro. Glia, 2012. http://dx.doi.org/10.1002/glia.22435
- B. Spittau, X. Zhou, M. Ming, K. Krieglstein: IL6 Protects MN9D Cells and Midbrain Dopaminergic Neurons from MPP(+)-Induced Neurodegeneration. Neuromol Med, 2012. http://dx.doi.org/10.1007/s12017-012-8189-7
- X. Zhou, B. Spittau, K. Krieglstein: TGFbeta signalling plays an important role in IL4-induced alternative activation of microglia. J Neuroinflamm, 2012; 9 (1), 210. http://dx.doi.org/10.1186/1742-2094-9-210
- R. Ouchida H. Mori K. Hase H. Takatsu, T. Kurosaki, T. Tokuhisa H. Ohno J.Y. Wang: Critical role of the IgM Fc receptor in IgM homeostasis, B-cell survival, and humoral immune responses. P Natl Acad Sci Usa, 2012. http://dx.doi.org/10.1073/pnas.1210706109
- T.D. Troutman, W. Hu, S. Fulenchek, T. Yamazaki,T. Kurosaki, J.F. Bazan, C. Pasare: Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt. P Natl Acad Sci Usa, 2012; 109 (1): 273-278. http://dx.doi.org/10.1073/pnas.1118579109
- T. Onodera, Y. Takahashi, Y. Yokoi, M. Ato, Y. Kodama, S. Hachimura, T. Kurosaki, K. Kobayashi: Memory B cells in the lung participate in protective humoral immune responses to pulmonary influenza virus reinfection. P Natl Acad Sci Usa, 2012; 109 (7): 2485-2490. http://dx.doi.org/10.1073/pnas.1115369109
- Y. Fujii, M. Shiota, Y. Ohkawa, A. Baba, H. Wanibuchi, T. Kinashi, T. Kurosaki, Y. Baba: Surf4 modulates STIM1-dependent calcium entry. Biochem Bioph Res Co, 2012. http://dx.doi.org/10.1016/j.bbrc.2012.05.037
- Y. Takahashi, T. Onodera, K. Kobayashi, T. Kurosaki: Primary and Secondary B-Cell Responses to Pulmonary Virus Infection. Infect Disord Drug Targets, 2012.
- E. Aichinger, N. Kornet, T. Friedrich, T. Laux: Plant Stem Cell Niches. Annual Review of Plant Biology, 2012; 63: 615-636.
- A. Joshi, Y. Beck, T. Michoel: Post-transcriptional regulatory networks play a key role in noise reduction which is conserved from micro-organisms to mammals. FEBS Journal, 2012; http://dx.doi.org/10.1111/j.1742-4658.2012.08571.x
- J. Qi, T. Michoel: Context-specific transcriptional regulatory network inference from global gene expression maps using double two-way t-tests. Bioinformatics, 2012; 28 (18): 2325-2332.
- J. Qi, T. Michoel, G. Butler: An Integrative Approach to Infer Regulation Programs in a Transcription Regulatory Module Network. Journal of Biomedicine and Biotechnology, 2012; http://dx.doi.org/10.1155/2012/245968
- M. Claeys, V. Storms, H. Sun, T. Michoel, K. Marchal: MotifSuite: workflow for probabilistic motif detection and assessment. Bioinformatics, 2012; 28 (14): 1931-1932.
- T. Michoel, B. Nachtergaele: Alignment and integration of complex networks by hypergraph-based spectral clustering. Physical Review E, 2012; 86 (5): 056111.
- B.H Cho, I. Cao-Berg, J.A. Bakal, R.F. Murphy: OMERO.searcher: content-based image search for microscope images. Nature Methods, 2012; 9 (7): 633-634.
- J. Li, L. Xiong, J. Schneider, R.F. Murphy: Protein subcellular location pattern classification in cellular images using latent discriminative models. Bioinformatics, 2012; 28 (12): i32-i39. http://dx.doi.org/10.1093/bioinformatics/bts230
- R.F. Murphy: CellOrganizer: Image-Derived Models of Subcellular Organization and Protein Distribution. Method Cell Biol, 2012; 110: 179-193. http://dx.doi.org/10.1016/B978-0-12-388403-9.00007-2
- R.F. Murphy, E. Komlodi-Pasztor, R. Robey, F.M. Balis, N.P. Farrell, T. Fojo: Retained platinum uptake and indifference to p53 status make novel transplatinum agents active in platinum-resistant cells compared to cisplatin and oxaliplatin. Cell Cycle, 2012; 11 (5).
- T. E. Buck, J. Li, G.K. Rohde, R.F. Murphy: Toward the virtual cell: Automated approaches to building models of subcellular organization "learned" from microscopy images. Bioessays, 2012; 34 (9): 791-799.
- A.E. Starr, A. Dufour, J. Maier, C.M. Overall: Biochemical analysis of matrix metalloproteinase activation of chemokines CCL15 and CCL23 and increased glycosaminoglycan binding of CCL16. J Biol Chem, 2012; 287 (8): 5948-5860. http://dx.doi.org/10.1074/jbc.M111.314609
- A.E. Starr, C.L. Bellac, A. Dufour, V. Goebeler, C.M. Overall: Biochemical characterization and N-terminomics analysis of leukolysin, the membrane-type 6 matrix metalloprotease (MMP25): chemokine and vimentin cleavages enhance cell migration and macrophase phagocytic activities. J Biol Chem, 2012; 287 (16): 13382-13395. http://dx.doi.org/10.1074/jbc.M111.314179
- C.D. Bosco, A. Dovzhenko, K. Palme: Intracellular auxin transport in pollen: PIN8, PIN5 and PILS5. Plant Signal Behav, 2012; 7 (11).
- C.D. Bosco, A. Dovzhenko, X. Liu, N. Woerner, T. Rensch, M. Eismann, S. Eimer, J. Hegermann, I.A. Paponov, B. Ruperti, E. Heberle-Bors, A. Touraev, J.D. Cohen, K. Palme: The endoplasmic reticulum localized PIN8 is a pollen specific auxin carrier involved in intracellular auxin homeostasis. Plant J , 2012. http://dx.doi.org/10.1111/j.1365-313X.2012.05037.x
- M.K. Singh, F. Ren, T. Giesemann, C.D. Bosco, T.P. Pasternak, T. Blein, B. Ruperti, G. Schmidt, K. Aktories, A.J. Molendijk, K. Palme: Modification of plant Rac/Rop GTPase signalling using bacterial toxin transgenes. Plant J, 2012. http://dx.doi.org/10.1111/tpj.12040
- N.S. Kiran, E. Benkova, A. Rekova, J. Dubova, J. Malbeck, K. Palme, B. Brzobohaty: Retargeting a maize beta-glucosidase to the vacuole - Evidence from intact plants that zeatin-O-glucoside is stored in the vacuole. Phytochemistry , 2012; 69: 67-77. http://dx.doi.org/10.1016/j.phytochem.2012.03.012
- S. Trevisan, A. Nonis, M. Begheldo, A. Manoli, K. Palme, G. Caporale, B. Ruperti, S. Quaggiotti: Expression and tissue-specific localization of nitrate-responsive miRNAs in roots of maize seedlings. Plant Cell Environ, 2012; 35 (6): 1137-1155. http://dx.doi.org/10.1111/j.1365-3040.2011.02478.x (in Druck)
- A. Erxleben, A. Gessler, M. Vervliet-Scheebaum, R. Reski: Metabolite profiling of the moss Physcomitrella patens reveals evolutionary conservation of osmoprotective substances. Plant Cell Rep, 2012; 31 (2): 427-436. http://dx.doi.org/10.1007/s00299-011-1177-9
- C. Kreutz, J.S. Gehring, D. Lang, R. Reski, J. Timmer, S.A. Rensing: TSSi - An R package for transcription start site identification from 5’ mRNA tag data. Bioinformatics, 2012; http://dx.doi.org/10.1093/bioinformatics/bts189.
- E. L. Decker, R. Reski: Glycoprotein production in moss bioreactors. Plant Cell Reports, 2012; 31: 453-460.
- H. Birke, S.J. Müller, M. Rother, A.D. Zimmer, S.N.W. Hoernstein, D. Wesenberg, M. Wirtz, G.-J. Krauss, R. Reski, R. Hell: The relevance of compartmentation for cysteine synthesis in phototrophic organisms. Protoplasma, 2012; doi: 10.1007/s00709-012-0411-9.
- J. Harba, O. Salehb, D. Kittemann, D.A. Neuwald, W. Frankd, R. Reski: Upregulation of polyphenol-related genes prevents ‘skin burning’ of well-colored ‘Cameo’ apples stored under stressful controlled atmosphere conditions. Postharvest Biol Tec, 2012: 1-7.
- J. Parsons, F. Altmann, C.K. Arrenberg, A. Koprivova, A.K. Beike, C. Stemmer, G. Gorr, R. Reski, E.L. Decker: Moss-based production of asialo-erythropoietin devoid of Lewis A and other plant-typical carbohydrate determinants. Plant Biotechnol J, 2012. http://dx.doi.org/10.1111/j.1467-7652.2012.00704.x
- J. Scholz, F. Brodhun, E. Hornung, C. Herrfurth, M. Stumpe, A.K. Beike, B. Faltin, W. Frank, R. Reski, I. Feussner: Biosynthesis of allene oxides in Physcomitrella patens. Bmc Plant Biol, 2012; 12 (1): 228. http://dx.doi.org/10.1186/1471-2229-12-228
- M.A. Arif, I. Fattash, Z. Ma, S.H. Cho, A.K. Beike, R. Reski, M.J. Axtell, W. Frank: DICER-LIKE3 Activity in Physcomitrella patens DICER-LIKE4 Mutants Causes Severe Developmental Dysfunction and Sterility. Mol Plant, 2012; 5 (6): 1281-1294. http://dx.doi.org/10.1093/mp/sss036
- M. T. Lehtonen, M. Akita, W. Frank, R. Reski, J.P.T. Valkonen: Involvement of a class III peroxidase and the mitochondrial protein TSPO in oxidative burst upon treatment of moss plants with a fungal elicitor. Molecular Plant-Microbe Interactions, 2012; 25: 363-371.
- S.Y. Kim, C.C. Colpitts, G. Wiedemann, C. Jepson, M. Rahimi, J.R. Rothwell, A.D. McInnes, T. Tanahashi, M. Hasebe, R. Reski, B.T. Sterenberg, D.-Y. Suh: Physcomitrella PpORS, basal to plant type III polyketide synthases in phylogenetic trees, is a very long chain 2’-oxoalkylresorcinol synthase. Journal of Biological Chemistry, 2012; http://www.jbc.org/cgi/doi/10.1074/jbc.M112.430686.
- A. Rodriguez, M. Schelker, M. Schilling, J. Bachmann, A. Raue, F. Salopiata, S. Depner, L. Adlung, R. Merkle, A. Franke, M. Jarsch, J. Timmer, U. Klingmueller: Epo and EpoR signaling dynamic in hematopoietic and tumor context. American Journal of Hematology, 2012; 87 (10): E116
- A. Yalcin, C. Kreutz, D. Pfeifer, M. Abdelkarim, G. Klaus, J. Timmer, M. Lubbert, B. Hackanson: MeDIP coupled with a promoter tiling array as a platform to investigate global DNA methylation patterns in AML cells. Leukemia Res, 2012. http://dx.doi.org/10.1016/j.leukres.2012.09.014
- B. Greese, K. Wester, R. Bensch, O. Ronneberger, J. Timmer, M. Huelskamp, C. Fleck: Influence of cell-to-cell variability on spatial pattern formation. IET Systems Biology, 2012; 6 (4): 143-153.
- B. Steiert, A. Raue, J. Timmer, C. Kreutz: Experimental design for parameter estimation of gene regulatory networks. Plos One, 2012; 7(7): e40052-e40052. http://dx.doi.org/10.1371/journal.pone.0040052
- C. Kreutz, A. Raue, J. Timmer: Likelihood based observability analysis and confidence intervals for predictions of dynamic models. Bmc Syst Biol, 2012; 6(1): 120. http://dx.doi.org/10.1186/1752-0509-6-120
- D. Kaschek, J. Timmer: A variational approach to parameter estimation in ordinary differential equations. Bmc Syst Biol, 2012; 6(1): 99. http://dx.doi.org/10.1186/1752-0509-6-99
- J. Bachmann, A. Raue, M. Schilling, V. Becker, J. Timmer, U. Klingmuller: Predictive Mathematical Models of Cancer Signalling Pathways. J Intern Med, 2012; 271 (2): 155-165. http://dx.doi.org/10.1111/j.1365-2796.2011.02492.x
- J. Klatt, H. Feldwisch-Drentrup, M. Ihle, V. Navarro, M. Neufang, C. Teixeira, C. Adam, M. Valderrama, C. Alvarado-Rojas, A. Witon, M. Le Van Quyen, F. Sales, A. Dourado, J. Timmer, A. Schulze-Bonhage, B. Schelter: The EPILEPSIAE database: An extensive electroencephalography database of epilepsy patients. Epilepsia, 2012; 53 (9): 1669-1676.
- K.S. Ferreira, C. Kreutz, S. Macnelly, K. Neubert, A. Haber, M. Bogyo, J. Timmer, C. Borner: Caspase-3 feeds back on caspase-8, Bid and XIAP in type I Fas signaling in primary mouse hepatocytes. Apoptosis, 2012; 17 (5): 503-515. http://dx.doi.org/10.1007/s10495-011-0691-0
- L. Sommerlade, B. Schelter, J. Timmer, M. Reinhard: Grading of Dynamic Cerebral Autoregulation Without Blood Pressure Recordings: A Simple Doppler-based Method. Ultrasound Med Biol , 2012. http://dx.doi.org/10.1016/j.ultrasmedbio.2012.05.003
- M. Ihle, H. Feldwisch-Dentrup, C.A. Teixeira, A. Witon, B. Schelter, J. Timmer, A. Schulze-Bonhage: EPILEPSIAE - A European epilepsy database. Computer Methods and Programs in Biomedicine, 2012; 106 (3): 127-138.
- M.M. Kampf, R. Engesser, M. Busacker, M. Horner, M. Karlsson, M.D. Zurbriggen, M. Fussenegger, J. Timmer, W. Weber: Rewiring and dosing of systems modules as a design approach for synthetic mammalian signaling networks. Mol Biosyst, 2012; 8 (6): 1824-1832. http://dx.doi.org/10.1039/c2mb05509k
- M. Schelker, A. Raue, J. Timmer, C. Kreutz: Comprehensive estimation of input signals and dynamics in biochemical reaction networks. Bioinformatics, 2012; 28 (18): I529-I534.
- R. Schlatter, N. Philippi, G. Wangorsch, R. Pick, O. Sawodny, C. Borner, J. Timmer, M. Ederer, T. Dandekar: Integration of Boolean models exemplified on hepatocyte signal transduction. Briefings in Bioinformatics, 2012; 13 (3): 365-376.
- T. Maiwald, J. Blumberg, A. Raue, S. Hengl, M. Schilling, S.K. Sy, V. Becker, U. Klingmuller, J. Timmer: In silico labeling reveals the time-dependent label half-life and transit-time in dynamical systems. Bmc Syst Biol, 2012; 6 (1): 13. http://dx.doi.org/10.1186/1752-0509-6-13
- V. Becker, J. Timmer, U. Klingmuller: Receptor dynamics in signaling. Adv Exp Med Biol, 2012; 736: 313-323. http://dx.doi.org/10.1007/978-1-4419-7210-1_18
- D. Fuchs-Telem, O. Sarig, M.A. van Steensel, O. Isakov, S. Israeli, J. Nousbeck, K. Richard, V. Winnepenninckx, M. Vernooij, N. Shomron, J. Uitto, P. Fleckman, G. Richard, E. Sprecher: Familial Pityriasis Rubra Pilaris Is Caused by Mutations in CARD14. Am J Hum Genet, 2012. http://dx.doi.org/10.1016/j.ajhg.2012.05.010
- E.A. Kupetsky-Rincon, Q. Li, J. Uitto: Magnesium reduces carotid intima-media thickness in a mouse model of pseudoxanthoma elasticum: a novel treatment biomarker. Clin Transl Sci, 2012; 5 (3): 259-264. http://dx.doi.org/10.1111/j.1752-8062.2011.00390.x
- E.A. Kupetsky-Rincon, J. Uitto: Magnesium: Novel Applications in Cardiovascular Disease - A Review of the Literature.Ann Nutr Metab, 2012; 61 (2): 102-110. http://dx.doi.org/10.1159/000339380
- J.C. Salas-Alanis, R. Cepeda-Valdes, J.E. Mellerio, A.M. Christiano, J. Uitto: Progress in epidermolysis bullosa: summary of a workshop in CILAD-2010*Int J Dermatol, 2012; 51 (6): 682-687. http://dx.doi.org/10.1111/j.1365-4632.2011.05130.x
- J. Uitto, C. Has, L. Bruckner-Tuderman: Cell-based therapies for epidermolysis bullosa - from bench to bedside.J Dtsch Dermatol Ges, 2012; 10 (11): 803-807. http://dx.doi.org/10.1111/j.1610-0387.2012.08035.x
- J. Uitto, U. Rodeck: Integration of investigative dermatology into the global biomedical research enterprise: past, present, and future. J Invest Dermatol, 2012; 132 (3 Pt 2): 1029-1032. http://dx.doi.org/10.1038/jid.2011.401
- J. Uitto, A.M. Christiano, W.H. McLean, J.A. McGrath: Novel Molecular Therapies for Heritable Skin Disorders. J Invest Dermatol, 2012; 132 (3 Pt 2): 820-828. http://dx.doi.org/10.1038/jid.2011.389
- J. Uitto: Rare heritable skin diseases: targets for regenerative medicine. J Invest Dermatol, 2012; 132 (11): 2485-2488. http://dx.doi.org/10.1038/jid.2012.334
- J. Uitto, Q. Li, Z. Urban: The complexity of elastic fibre biogenesis in the skin - a perspective to the clinical heterogeneity of cutis laxa. Exp Dermatol, 2012. http://dx.doi.org/10.1111/exd.12025
- M. El-Domyati, T.S. El-Ammawi, W. Medhat, O. Moawad, M.G. Mahoney, J. Uitto: Multiple minimally invasive Erbium: Yttrium Aluminum Garnet laser mini-peels for skin rejuvenation: an objective assessment. J Cosmet Dermatol, 2012; 11 (2): 122-130. http://dx.doi.org/10.1111/j.1473-2165.2012.00606.x
- N.B. Kavukcuoglu, Q. Li, N. Pleshko, J. Uitto: Connective tissue mineralization in Abcc6(-/-) mice, a model for pseudoxanthoma elasticum., Matrix Biol, 2012; 31 (4): 246-252. http://dx.doi.org/10.1016/j.matbio.2012.02.004
- Q. Jiang, J. Uitto: Restricting dietary magnesium accelerates ectopic connective tissue mineralization in a mouse model of pseudoxanthoma elasticum (Abcc6(-/-) ).Exp Dermatol, 2012; 21 (9): 694-699. http://dx.doi.org/10.1111/j.1600-0625.2012.01553.x
- Q. Li, H. Guo, H. Matsui, H. Honda, T. Inaba, J.P. Sundberg, E. Sprecher, J. Uitto: Mouse Samd9l is not a functional paralogue of the human SAMD9, the gene mutated in normophosphataemic familial tumoral calcinosis.Exp Dermatol, 2012; 21 (7): 554-556. http://dx.doi.org/10.1111/j.1600-0625.2012.01524.x
- H. Tsuboi, S. Nakamura, E. Schaefer, M. Wada: Red Light-Induced Phytochrome Relocation into the Nucleus in Adiantum capillus-veneris. MOLECULAR PLANT, 2012; 5 (3): 611-618.