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Elias August: "Closing the Cycle: From Experiment Design to Data and Model Analysis to Experiment Design"

Wann 12.03.2010
von 11:15 bis 12:00
Wo FRIAS Seminarraum, Albertstr. 19, 79104 Freiburg
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Dr. Elias August
Department of Computer Science, Pattern Analysis & Machine Learning Group, ETH Zurich

 

Closing the Cycle: From Experiment Design to Data and Model Analysis to Experiment Design

Given biological data different mathematical models might explain equally well the observations made. Thus, an important task is to develop a methodology to design a new experiment that will allow distinguishing best between the rivaling models. The first part of my talk will focus on such a procedure. The second part will present a method to test a priori whether an experiment will provide the information (the model parameter values or reaction rates) sought after. Finally, in the last part, I will elabo-rate on a computational approach to elucidate the biochemical network structure from experimental data.