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Publications 2013


Scientific Journals:

  1. J. Speck, C. Rauber, T. Kukenshoner, C. Niemoller, K.J. Mueller, P. Schleberger, P. Dondapati, J. Hecky, K.M. Arndt, K.M. Muller: TAT hitchhiker selection expanded to folding helpers, multimeric interactions and combinations with protein fragment complementation. Protein Eng Des Sel, 2013; 26 (3): 225-242.
  2. A. Nystrom, L. Bruckner-Tuderman, J.S. Kern: Cell- and protein-based therapy approaches for epidermolysis bullosa. Methods Mol Biol, 2013; 961: 425-440.
  3. A. Nystrom, D. Velati, V.R. Mittapalli, A. Fritsch, J.S. Kern, L. Bruckner-Tuderman: C7 plays a dual role in skin wound healing. J Invest Dermatol, 2013; 133 Suppl. 1: S256-S256.
  4. A. Nystrom, D. Velati, V.R. Mittapalli, J.S. Kern, A. Fritsch, L. Bruckner-Tuderman: Collagen VII plays a dual role in wound healing. J Clin Invest, 2013. (in press)
  5. A. Nystrom, J. Buttgereit, M. Bader, T. Shmidt, C. Ozcelik, I. Hausser, L. Bruckner-Tuderman, J.S. Kern: Rat Model for Dominant Dystrophic Epidermolysis Bullosa: Glycine Substitution Reduces Collagen VII Stability and Shows Gene-Dosage Effect. Plos One, 2013; 8 (5): e64243-e64243.
  6. A. Sprenger, V. Kuttner, L. Bruckner-Tuderman, J. Dengjel: Global Proteome Analyses of SILAC-Labeled Skin Cells. Methods Mol Biol, 2013; 961: 179-191.
  7. C. Hunefeld, M. Mezger, J.S. Kern, A. Nystrom, L. Bruckner-Tuderman, R. Handgretinger, M. Rocken: One goal, different strategies - molecular and cellular approaches for the treatment of inherited skin fragility disorders. Exp Dermatol, 2013; 22(3): 162-167.
  8. D. Kiritsi, M. Pigors, I. Tantcheva-Poor, C. Wessel, M.J. Arin, J. Kohlhase, L. Bruckner-Tuderman, C. Has: Epidermolysis bullosa simplex ogna revisited. J Invest Dermatol, 2013; 133 (1): 270-273.
  9. S.C. Hofmann, A. Bosma, L. Bruckner-Tuderman, M. Vukmanovic-Stejic, E.C. Jury, D.A. Isenberg, C. Mauri: Invariant natural killer T cells are enriched at the site of cutaneous inflammation in lupus erythematosus. J Dermatol Sci, 2013; 71 (1): 22-28.
  10. V. Küttner, C. Mack, K. TG Rigbolt, J. S Kern, O. Schilling, H. Busch, L. Bruckner-Tuderman, J. Dengjel: Global remodelling of cellular microenvironment due to loss of collagen VII. Molecular Systems Biology, 2013.
  11. V.I. Dumit, V. Kuttner, J. Kappler, S. Piera-Velazquez, S.A. Jimenez, L. Bruckner-Tuderman,J. Uitto, J. Dengjel: Resemblances between scleroderma and ageing in skin fibroblasts. J Invest Dermatol, 2013; 133 Suppl. 1: S156-S156.
  12. A. Sprenger, S. Weber, M. Zarei, R. Engelke, J.M. Nascimento, C. Gretzmeier, M. Hilpert, M. Boerries, C. Has,H. Busch, L. Bruckner-Tuderman, J. Dengjel: Consistency of the proteome in primary human keratinocytes with respect to gender, age, and skin localization. Mol Cell Proteomics, 2013.
  13. H. Busch, M. Boerries, J. Bao, S.T. Hanke, M. Hiss, T. Tiko, S.A. Rensing: Network theory inspired analysis of time-resolved expression data reveals key players guiding P. patens stem cell development. Plos One, 2013; 8 (4): e60494-e60494.
  14. M. Boerries, F. Grahammer, S. Eiselein, M. Buck, C. Meyer, M. Goedel, W. Bechtel, S. Zschiedrich, D. Pfeifer, D. Laloe, C. Arrondel, S. Goncalves, M. Kruger, S.J. Harvey, H. Busch, J. Dengjel, T.B. Huber: Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks. Kidney Int, 2013.
  15. M. Buck, D. Saltukoglu, M. Boerries, M. Simons, H. Busch: A distributed stochastic perception-action loop model of cell motility. IEEE Conference Proceedings, 2013. [in Druck]
  16. S. Tholen, M.L. Biniossek, M. Gansz, A. Gomez-Auli, F. Bengsch, A. Noel, J.N. Kizhakkedathu, M. Boerries, H. Busch, T. Reinheckel, O. Schilling: Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome. Mol Cell Proteomics, 2013; 12 (3): 611-625.
  17. F. Nazio, F. Strappazzon, M. Antonioli, P. Bielli, V. Cianfanelli, M. Bordi, C. Gretzmeier, J. Dengjel, M. Piacentini, G.M. Fimia, F. Cecconi: mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6. Nat Cell Biol, 2013; 15 (4): 406-416.
  18. M. Fischer, S. Horn, A. Belkacemi, K. Kojer, C. Petrungaro, M. Habich, m. Ali, V. Kuttner, M. Bien, F. Kauff, J. Dengjel, J.M. Herrmann, J. Riemer: Protein import and oxidative folding in the mitochondrial intermembrane space of intact mammalian cells. Mol Biol Cell, 2013.
  19. S. Halbach, K.T. Rigbolt, F.U. Wohrle, B. Diedrich, C. Gretzmeier, T. Brummer, J. Dengjel: Alterations of Gab2 signalling complexes in imatinib and dasatinib treated chronic myeloid leukaemia cells. Cell Commun Signal, 2013; 11 (1): 30-30.
  20. J. Schweitzer, H. Lohr, J.L. Bonkowsky, K. Hubscher, W. Driever: Sim1a and Arnt2 contribute to hypothalamo-spinal axon guidance by regulating Robo2 activity via a Robo3-dependent mechanism. Development, 2013; 140 (1): 93-106.
  21. S. Song, S. Eckerle, D. Onichtchouk, J.A. Marrs, R. Nitschke, W. Driever: Pou5f1-Dependent EGF Expression Controls E-Cadherin Endocytosis, Cell Adhesion, and Zebrafish Epiboly Movements. Developmental Cell, 2013; 24 (5): 486-501.
  22. H.P. Ren, M.S. Baptista, C. Grebogi: Wireless communication with chaos. Phys Rev Lett, 2013; 110 (18): 184101.
  23. H. Xu, L. Huang, Y.C. Lai, C. Grebogi: Chiral scars in chaotic dirac fermion systems. Phys Rev Lett, 2013; 110 (6): 064102.
  24. R. Yang, L. Huang, Y.C. Lai, C. Grebogi, L.M. Pecora: Harnessing quantum transport by transient chaos. Chaos, 2013; 23 (1): 013125.
  25. A. Sharaf, K. Krieglstein, B. Spittau: Distribution of microglia in the postnatal murine nigrostriatal system. Cell Tissue Res, 2013; 351 (3): 373-382. :
  26. B. Spittau, L. Wullkopf, X. Zhou, J. Rilka, D. Pfeifer, K. Krieglstein: Endogenous transforming growth factor-beta promotes quiescence of primary microglia in vitro. Glia, 2013; 61 (2): 287-300. :
  27. S. Heermann, K. Matlik, U. Hinz, J. Fey, U. Arumae, K. Krieglstein: Glia cell line-derived neurotrophic factor mediates survival of murine sympathetic precursors. J Neurosci Res, 2013. :
  28. S. Knauer, A.L. Holt, I. Rubio-Somoza, E.J. Tucker, A. Hinze, M. Pisch, M. Javelle, M.C. Timmermans, M.R. Tucker, T. Laux: A protodermal miR394 signal defines a region of stem cell competence in the Arabidopsis shoot meristem. Dev Cell, 2013; 24 (2): 125-132.
  29. S. Demeyer, T. Michoel, J. Fostier, P. Audenaert, M. Pickavet, P. Demeester: The Index-Based Subgraph Matching Algorithm (ISMA): Fast Subgraph Enumeration in Large Networks Using Optimized Search Trees. Plos One, 2013; 8 (4): e61183-e61183.
  30. C. Stadler, E. Rexhepaj, V.R. Singan, R.F. Murphy, R. Pepperkok, M. Uhlen, J.C. Simpson, E. Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. Nat Methods, 2013.
  31. S. Weber, M.L. Fernandez-Cachon, J.M. Nascimento, S. Knauer, B. Offermann, R.F. Murphy, M. Boerries, H. Busch: Label-Free Detection of Neuronal Differentiation in Cell Populations Using High-Throughput Live-Cell Imaging of PC12 Cells Plos One, 2013; 8: e56690.
  32. M.K. Singh, F. Ren, T. Giesemann, C.D. Bosco, T.P. Pasternak, T. Blein, B. Ruperti, G. Schmidt, K. Aktories, A.J. Molendijk, K. Palme: Modification of plant Rac/Rop GTPase signalling using bacterial toxin transgenes. Plant J, 2013; 73 (2): 314-324.
  33. S. Rigas, F.A. Ditengou, K. Ljung, G. Daras, O. Tietz, K. Palme, P. Hatzopoulos: Root gravitropism and root hair development constitute coupled developmental responses regulated by auxin homeostasis in the Arabidopsis root apex. New Phytol, 2013; 197 (4): 1130-1141.
  34. J. Harb, O. Saleh, D. Kittemann, D.A. Neuwald, W. Frank, R. Reski: Upregulation of polyphenol-related genes prevents ‘skin burning’ of well-colored ‘Cameo’ apples stored under stressful controlled atmosphere conditions. Postharvest Biol Tec, 2013; 77: 121-127.
  35. L. Cooper, R.L. Walls, J. Elser, M.A. Gandolfo, D.W. Stevenson, B. Smith, J. Preece, B. Athreya, C.J. Mungall, S. Rensing, M. Hiss, D. Lang, R. Reski, T.Z. Berardini, D. Li, E. Huala, M. Schaeffer, N. Menda, E. Arnaud, R. Shrestha, Y. Yamazaki, P. Jaiswal: The Plant Ontology as a tool for comparative plant anatomy and genomic analyses. Plant and Cell Physiology, 2013; 54 (2): 1-23. doi: 10.1093/pcp/pcs163
  36. N. Wangler, M. Welsche, M. Blazek, M. Blessing, M. Vervliet-Scheebaum, R. Reski, C. Muller, H. Reinecke, J. Steigert, G. Roth, R. Zengerle, N. Paust: Bubble Jet agent release cartridge for chemical single cell stimulation. Biomed Microdevices, 2013; 15 (1): 1-8.
  37. S.Y. Kim, C.C. Colpitts, G. Wiedemann, C. Jepson, M. Rahimi, J.R. Rothwell, A.D. McInnes, M. Hasebe, R. Reski, B.T. Sterenberg, D.Y. Suh: Physcomitrella PpORS, basal to plant type III polyketide synthases in phylogenetic trees, is a very long chain 2'-oxoalkylresorcinol synthase. J Biol Chem, 2013; 288 (4): 2767-2777.
  38. A. Yalcin, C. Kreutz, D. Pfeifer, M. Abdelkarim, G. Klaus, J. Timmer, M. Lubbert, B. Hackanson: MeDIP coupled with a promoter tiling array as a platform to investigate global DNA methylation patterns in AML cells. Leukemia Res, 2013; 37 (1): 102-111.
  39. A. Raue, C. Kreutz, F.J. Theis, J. Timmer: Joining forces of Bayesian and frequentist methodology: a study for inference in the presence of non-identifiability. Philos T Roy Soc A, 2013; 371 (1984): 20110544-20110544.
  40. C. Kreutz, A. Raue, D. Kaschek, J. Timmer: Profile likelihood in systems biology. Febs J, 2013; 280 (11): 2564-2571.
  41. K. Aumann, A.V. Frey, A.M. May, D. Hauschke, C. Kreutz, J.P. Marx, J. Timmer, M. Werner, H.L. Pahl: Subcellular mislocalization of the transcription factor NF-E2 in erythroid cells discriminates pre-fibrotic primary myelofibrosis from essential thrombocythemia. Blood, 2013.
  42. K. Muller, R. Engesser, S. Metzger, S. Schulz, M.M. Kampf, M. Busacker, T. Steinberg, P. Tomakidi, M. Ehrbar, F. Nagy, J. Timmer, M.D. Zubriggen, W. Weber: A red/far-red light-responsive bi-stable toggle switch to control gene expression in mammalian cells. Nucleic Acids Res, 2013.
  43. K. Muller, R. Engesser, S. Schulz, T. Steinberg, P. Tomakidi, C.C. Weber, R. Ulm, J. Timmer M.D. Zurbriggen, W. Weber: Multi-chromatic control of mammalian gene expression and signaling. Nucleic Acids Res, 2013.
  44. M. Mischnik, D. Boyanova, K. Hubertus, J. Geiger, N. Philippi, M. Dittrich, G. Wangorsch, J. Timmer, T. Dandekar: A Boolean view separates platelet activatory and inhibitory signalling as verified by phosphorylation monitoring including threshold behaviour and integrin modulation. Mol Biosyst, 2013. :
  45. V. Morath, M. Keuper, M. Rodriguez-Franco, S. Deswal, G. Fiala, B. Blumenthal, D. Kaschek, J. Timmer, G. Neuhaus, S. Ehl, O. Ronneberger, W.W. Schamel: Semi-automatic determination of cell surface areas used in systems biology . Front Biosci (Elite Ed), 2013; 5: 533-545.
  46. G. Akoglu, Q. Li, O. Gokoz, A.S. Gazyagci, J. Uitto: Clinical and histopathological characteristics of a family with R1141X mutation of pseudoxanthoma elasticum - presymptomatic testing and lack of carrier phenotypes. Int J Dermatol, 2013. href="
  47. J. Uitto, A. Varadi, L. Bercovitch, P.F. Terry, S.F. Terry: Pseudoxanthoma Elasticum: Progress in Research Toward Treatment: Summary of the 2012 PXE International Research Meeting. J Invest Dermatol, 2013; 133 (6): 1444-1449.
  48. M. El-Domyati, T.S. El-Ammawi, W. Medhat, O. Moawad, M.G. Mahoney, J. Uitto: Expression of p53 Protein After Nonablative Rejuvenation: The Other Side of the Coin. Dermatol Surg, 2013. :
  49. C.S. Faria, Q. Li, H. Guo, J. Uitto, S.S. Takeno, S.M. de Arruda Cardoso, D.V. Freire-Maia: Clinical Phenotypes and ABCC6 Gene Mutations in Brazilian Families with Pseudoxanthoma Elasticum. Acta Derm-venereol, 2013. :
  50. Q. Li, H. Guo, D. Chou, D.J. Harrington, L.J. Schurgers, S.F. Terry, J. Uitto: Warfarin Accelerates Ectopic Mineralization in Abcc6(-/-) Mice: Clinical Relevance to Pseudoxanthoma Elasticum. Am J Pathol, 2013. :
  51. Q. Li, J. Uitto: Mineralization/Anti-Mineralization Networks in the Skin and Vascular Connective Tissues. Am J Pathol, 2013.
  52. Q. Li, J. Uitto: Zebrafish as a model system to study heritable skin diseases. Methods Mol Biol, 2013; 961: 411-424.
  53. V. Alexeev, A. Donahue, J. Uitto, O. Igoucheva: Analysis of chemotactic molecules in bone marrow-derived mesenchymal stem cells and the skin: Ccl27-Ccr10 axis as a basis for targeting to cutaneous tissues. Cytotherapy, 2013; 15 (2): 171-184.e1.
  54. X. Wang, P. Ghasri, M. Amir, B. Hwang, Y. Hou, M. Khilili, A. Lin, D. Keene, J. Uitto, D.T. Woodley, M. Chen: Topical Application of Recombinant Type VII Collagen Incorporates Into the Dermal-Epidermal Junction and Promotes Wound Closure. Mol Ther, 2013.
  55. Y. Zhou, Q. Jiang, S. Takahagi, C. Shao, J. Uitto: Premature Termination Codon Read-Through in the ABCC6 Gene: Potential Treatment for Pseudoxanthoma Elasticum. J Invest Dermatol, 2013.


Scientific Staff:

  1. A.C. Alvarez, G. Hime, J.D. Silva, D. Marchesin: Analytic regularization of an inverse filtration problem in porous media. Inverse Problems, 2013; 29 (2): 025006.