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Publikationen Natur- und Ingenieurwissenschaften 2016
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Originalarbeiten in wissenschaftlichen Fachzeitschriften Jahre: 2016 | alle anzeigen zurück zur Übersicht aller Publikationen Belyy A , Levanova N , Tabakova I , Rospert S , Belyi Y Ribosomal protein Rps26 influences 80S ribosome assembly in Saccharomyces cerevisiae 2016 mSphere , Band : 17, Nummer : 1, Ergänzungsband : 1Wang H , Li X , .... , Palme K , Ditengou F 2-D Clinostat for Simulated Microgravity Experiments with Arabidopsis Seedlings (vol 28, pg 59, 2016) 2016 MICROGRAVITY SCIENCE AND TECHNOLOGY , Band : 28, Nummer : 3Hügle M , Lucas X , Weitzel G , Ostrovskyi D , Breit B , Gerhard S , Einsle O , Günther S , Wohlwend D 4-Acyl Pyrrole Derivatives Yield Novel Vectors for Designing Inhibitors of the Acetyl-Lysine Recognition Site of BRD4((1) 2016 J Med Chem , Band : 59, Seiten : 1518 - 1530Morera L , Roatsch M , ... , Heinrich MR , Jung M 4‐Biphenylalanine‐ and 3‐Phenyltyrosine‐Derived Hydroxamic Acids as Inhibitors of the JumonjiC‐Domain‐Containing Histone Demethylase KDM4A 2016 Chemmedchem , Band : 11, Nummer : 18, Seiten : 2063 - 2083Boehler C , Guder F , Kucukbayrak UM , Zacharias M , Asplund M A Simple Approach for Molecular Controlled Release based on Atomic Layer Deposition Hybridized Organic-Inorganic Layers. 2016 Sci Rep-uk , Band : 6, Seiten : 19574 - 19574Pinnell R , Almajidy R , Kirch R , Cassel J , Hofmann U A Wireless EEG Recording Method for Rat Use inside the Water Maze 2016 PLOS ONE , Band : 11, Nummer : 2Galleano I , Schiedel M , Jung M , Madsen AS , Olsen CA A continuous, fluorogenic Sirtuin 2 deacylase assay 2016 J Med Chem , Band : 59, Seiten : 1021 - 1031Grahammer F , ... , Boerries M , ... , Huber TB A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes. 2016 JCI Insight , Band : 1, Nummer : 9Brown M , McKernan J , Svaldi R , Runpu Z A geometric characterisation
of toric varieties 2016 arXiv:1605.08911 Haas J , Schätzle MA , Husain SM , Schulz-Fincke J , Jung M , Hummel W , Müller M , Lüdeke S A quinone mediator drives oxidations catalysed by alcohol dehydrogenase-containing cell lysate 2016 Chem Commun , Band : 52, Seiten : 5198 - 5201Horst NA , Katz A , Pereman I , Decker EL , Ohad N , Reski R A single homeobox gene triggers phase transition, embryogenesis and asexual reproduction. 2016 Nat Plants , Band : 2, Seiten : 15209 - 15209Gandola E , Antonioli M , Traficante A , Franceschini S , Scardi M , Congestri R ACQUA: Automated Cyanobacterial Quantification Algorithm for toxic filamentous genera using spline curves, pattern recognition and machine learning. 2016 J Microbiol Meth , Band : 124, Seiten : 48 - 56Aktories K , Schwan C , Lang AE ADP-Ribosylation and Cross-Linking of Actin by Bacterial Protein Toxins. 2016 Handb Exp Pharmacol Grahammer F , Huber TB Aberrant podocyte cell cycle in glomerular disease. 2016 Cell Cycle , Seiten : 1 - 2Lang AE , Qu Z , Schwan C , Silvan U , Unger A , Schoenenberger CA , Aktories K , Mannherz HG Actin ADP-ribosylation at Threonine148 by Photorhabdus luminescens toxin TccC3 induces aggregation of intracellular F-actin. 2016 Cell Microbiol Naik AW , Kangas JD , Sullivan DP , Murphy RF Active machine learning-driven experimentation to determine compound effects on protein patterns. 2016 Elife , Band : 5, Seiten : e10047 - e10047Bateni A , Erdem E , Repp S , Weber S , Somer M Al-doped MgB2 materials studied using electron paramagnetic resonance and Raman spectroscopy 2016 APPLIED PHYSICS LETTERS , Band : 108, Nummer : 20» Kurzfassung anzeigen « Kurzfassung verbergen Kurzfassung Undoped and aluminum (Al) doped magnesium diboride (MgB2) samples were synthesized using a high-temperature solid-state synthesis method. The microscopic defect structures of Al-doped MgB2 samples were systematically investigated using X-ray powder diffraction, Raman spectroscopy, and electron paramagnetic resonance. It was found that Mg-vacancies are responsible for defect-induced peculiarities in MgB2. Above a certain level of Al doping, enhanced conductive properties of MgB2 disappear due to filling of vacancies or trapping of Al in Mg-related vacancy sites. Published by AIP Publishing.Schiedel M , Rumpf T , Karaman B , Lehotzky A , Olah A , Gerhardt S , Ovádi J , Sippl W , Einsle O , Jung M Aminothiazoles as potent and selective Sirt2 inhibitors – a structure-activity relationship study 2016 J Med Chem , Band : 59, Seiten : 1599 - 1612Schopf A , Boehler C , Asplund M Analytical methods to determine electrochemical factors in electrotaxis setups and their implications for experimental design. 2016 Bioelectrochemistry , Band : 109, Seiten : 41 - 48Baluschev S Annihilation upconversion in nanoconfinement: solving the oxygen quenching problem 2016 Mater Horiz , Band : 3, Seiten : 478 - 486Mielenz M , Kalis H , ... , Moehring DL , Leibfried D , Schaetz T Arrays of individually controlled ions suitable for two-dimensional quantum simulations. 2016 Nat Commun , Band : 7, Seiten : ncomms11839 - ncomms11839Metzger E , Willmann D , McMillan J , Forne I , Metzger P , Gerhardt S , Petroll K , von Maessenhausen A , Urban S , Schott A-K , Espejo A , Eberlin A , Wohlwend D , Schüle KM , Schleicher M , Perner S , Bedford MT , Jung M , Dengjel J , Flaig R , Imhof A , Einsle O , Schüle R Assembly of methylated LSD1 and CHD1 drives AR dependent transcription and translocation 2016 Nat Struct Mol Biol , Band : 23, Seiten : 132 - 139Xu K , Wang YH , Khakyzadeh V , Breit B Asymmetric Synthesis of Allylic Amines via Hydroamination of Allenes with Benzophenone Imine 2016 Chem Sci , Seiten : 3313 - 3316Garcia-Masso Xavier , Huber Matthias , Friedmann Jacqueline. , Gonzalez Luis , Schiller Stefan , Toca-Herrera Jose Automated detection of protein unfolding events in atomic force microscopy force curves 2016 MICROSCOPY RESEARCH AND TECHNIQUE , Band : 79, Nummer : 11, Seiten : 1105 - 1111Garcia-Masso X , Huber MC , Friedmann J , Gonzalez LM , Schiller SM , Toca-Herrera JL Automated detection of protein unfolding events in atomic force microscopy force curves. 2016 Microsc Res Techniq , Band : 79, Nummer : 11, Seiten : 1105 - 1111Lenoir O , Tharaux PL , Huber TB Autophagy in kidney disease and aging: lessons from rodent models. 2016 Kidney Int Halbach S , Hu Z , Gretzmeier C , Ellermann J , Wohrle FU , Dengjel J , Brummer T Axitinib and sorafenib are potent in tyrosine kinase inhibitor resistant chronic myeloid leukemia cells. 2016 Cell Commun Signal , Band : 14, Seiten : 6 - 6Thorwart M BCS theory of driven superconductivity 2016 Eur Phys J B , Band : 89, Nummer : 244Komnik A , Thorwart M BCS theory of driven superconductivity 2016 EUROPEAN PHYSICAL JOURNAL B , Band : 89, Nummer : 11Campana F Benoît Quelques propriétés de stabilité des variétés spéciales. 2016 Math Z , Band : 283, Nummer : 1, Seiten : 581 - 599Conradt D , Hermann B , Gerhardt S , Einsle O , Müller M Biocatalytic properties and structural analysis of phologlucinol reductases 2016 Angew. Chem. Intl. Ed. , Band : 55, Seiten : 15531 - 15534Koschker P , Breit B Branching Out: Rhodium-Catalyzed Allylation with Alkynes and Allenes 2016 Acc. Chem. Res. , Band : 49, Seiten : 1524 - 1536Murphy RF Building cell models and simulations from microscope images. 2016 Methods , Band : 96, Seiten : 33 - 39Mueller S , Guetle D , Jacquot JP , Reski R Can mosses serve as model organisms for forest research? 2016 ANNALS OF FOREST SCIENCE , Band : 73, Nummer : 1, Seiten : 135 - 146» Kurzfassung anzeigen « Kurzfassung verbergen Kurzfassung Context and aims Mosses are important components of several ecosystems. The moss P. patens is a well-established non-vascular model plant with a high amenability to molecular biology techniques and was designated as a JGI plant flagship genome. In this review, we will provide an introduction to moss research and highlight the characteristics of P. patens and other mosses as a potential complementary model system for forest research. Methods Starting with an introduction into general moss biology, we summarize the knowledge about moss physiology and differences to seed plants. We provide an overview of the current research areas utilizing mosses, pinpointing potential links to tree biology. To complement literature review, we discuss moss advantages and available resources regarding molecular biology techniques. Results and conclusion During the last decade, many fundamental processes and cell mechanisms have been studied in mosses and seed plants, increasing our knowledge of plant evolution. Additionally, moss-specific mechanisms of stress tolerance are under investigation to understand their resilience in ecosystems. Thus, using the advantages of model mosses such as P. patens is of high interest for various research approaches, including stress tolerance, organelle biology, cell polarity, and secondary metabolism.Eisenberg T , ... , Dengjel J , ... , Madeo F Cardioprotection and lifespan extension by the natural polyamine spermidine. 2016 Nat Med Quast R , Ballion B , ... , Schiller S , Kubick S Cell-free synthesis of functional human epidermal growth factor receptor: Investigation of ligand-independent dimerization in Sf21 microsomal membranes using non-canonical amino acids 2016 SCIENTIFIC REPORTS , Band : 6Wellens T , Jalabert RA Charge and spin diffusion in the metallic side of the metal-insulator transition: a self-consistent approach 2016 Phys Rev B , Band : 94Pham CV , Repp S , Thomann R , Krueger M , Weber S , Erdem E Charge transfer and surface defect healing within ZnO nanoparticle decorated graphene hybrid materials. 2016 Nanoscale , Band : 8, Nummer : 18, Seiten : 9682 - 9687Gonzalez AG , Jimenez-Villacorta F , Beike AK , Reski R , Adamo P , Pokrovsky OS Chemical and structural characterization of copper adsorbed on mosses (Bryophyta). 2016 J Hazard Mater , Band : 308, Seiten : 343 - 354Gütle DD , ... , Reski R , Einsle O , Jacquot JP Chloroplast FBPase and SBPase are thioredoxin-linked enzymes with similar architecture but different evolutionary histories 2016 Proc. Natl. Acad. Sci. USA , Band : 113, Seiten : 6779 - 6784Pöltl Ch , Kozikov A , Ensslin K , Ihn T , Jalabert RA , Reichl Ch , Wegscheider W , Weinmann D Classical origin of conductance oscillations in an integrable cavity 2016 Phys Rev B , Band : 94Kahl L , Hofmann U Comparison of algorithms to quantify muscle fatigue in upper limb muscles based on sEMG signals 2016 MEDICAL ENGINEERING & PHYSICS , Band : 38, Nummer : 11, SI, Seiten : 1260 - 1269Roybal KT , Buck TE , Ruan X , Cho BH , Clark DJ , Ambler R , Tunbridge HM , Zhang J , Verkade P , Wulfing C , Murphy RF Computational spatiotemporal analysis identifies WAVE2 and cofilin as joint regulators of costimulation-mediated T cell actin dynamics. 2016 Sci Signal , Band : 9, Nummer : 424, Seiten : rs3 - rs3Rieger SB , Pfau J , Stieglitz T , Asplund M , Ordonez JS Concept and Development of an Electronic Framework Intended for Electrode and Surrounding Environment Characterization In Vivo. 2016 Sensors-basel , Band : 17, Nummer : 1Ma Z , Park S , ... , Tabata O Constructing higher order DNA origami arrays using DNA junctions of anti-parallel/parallel double crossovers 2016 JAPANESE JOURNAL OF APPLIED PHYSICS , Band : 55, Nummer : 6, 1» Kurzfassung anzeigen « Kurzfassung verbergen Kurzfassung DNA origami provides a versatile method for the construction of nanostructures with defined shape, size and other properties; such nanostructures may enable a hierarchical assembly of large scale architecture for the placement of other nanomaterials with atomic precision. However, the effective use of these higher order structures as functional components depends on knowledge of their assembly behavior and mechanical properties. This paper demonstrates construction of higher order DNA origami arrays with controlled orientations based on the formation of two types of DNA junctions: anti-parallel and parallel double crossovers. A two-step assembly process, in which preformed rectangular DNA origami monomer structures themselves undergo further self-assembly to form numerically unlimited arrays, was investigated to reveal the influences of assembly parameters. AFM observations showed that when parallel double crossover DNA junctions are used, the assembly of DNA origami arrays occurs with fewer monomers than for structures formed using anti-parallel double crossovers, given the same assembly parameters, indicating that the configuration of parallel double crossovers is not energetically preferred. However, the direct measurement by AFM force-controlled mapping shows that both DNA junctions of anti-parallel and parallel double crossovers have homogeneous mechanical stability with any part of DNA origami. (C) 2016 The Japan Society of Applied PhysicsLi J , Leyva-Castillo JM , Hener P , Eisenmann A , Zaafouri S , Jonca N , Serre G , Birling MC , Li M Counterregulation between thymic stromal lymphopoietin- and IL-23-driven immune axes shapes skin inflammation in mice with epidermal barrier defects. 2016 J Allergy Clin Immun , Band : 138, Nummer : 1, Seiten : 150 - 161.e13Schuergers N , Lenn T , Kampmann R , Meissner MV , Esteves T , Temerinac-Ott M , Korvink JG , Lowe AR , Mullineaux CW , Wilde A Cyanobacteria use micro-optics to sense light direction. 2016 Elife , Band : 5:e12620Gandola E , Antonioli M , Traficante A , Franceschini S , Scardi M , Congestri R Dataset exploited for the development and validation of automated cyanobacteria quantification algorithm, ACQUA. 2016 Data Brief , Band : 8, Seiten : 817 - 823Repp S , Weber S , Erdem E Defect Evolution of Nonstoichiometric ZnO Quantum Dots 2016 JOURNAL OF PHYSICAL CHEMISTRY C , Band : 120, Nummer : 43, Seiten : 25124 - 25130Skourtis SS , Liu C , Antoniou P , Virshup AM , Beratan DN Dexter energy transfer pathways. 2016 P Natl Acad Sci Usa , Band : 113, Nummer : 29, Seiten : 8115 - 8120Daniels IN , Wang Z , Laird BB Dielectric Properties of Organic Solvents in an Electric Field 2016 J Phys Chem C Azhar M , Greiner A , Korvink JG , Kauzlaric D Dissipative particle dynamics of diffusion-NMR requires high Schmidt-numbers 2016 JOURNAL OF CHEMICAL PHYSICS , Band : 144, Nummer : 24» Kurzfassung anzeigen « Kurzfassung verbergen Kurzfassung We present an efficient mesoscale model to simulate the diffusion measurement with nuclear magnetic resonance (NMR). On the level of mesoscopic thermal motion of fluid particles, we couple the Bloch equations with dissipative particle dynamics (DPD). Thereby we establish a physically consistent scaling relation between the diffusion constant measured for DPD-particles and the diffusion constant of a real fluid. The latter is based on a splitting into a centre-of-mass contribution represented by DPD, and an internal contribution which is not resolved in the DPD-level of description. As a consequence, simulating the centre-of-mass contribution with DPD requires high Schmidt numbers. After a verification for fundamental pulse sequences, we apply the NMR-DPD method to NMR diffusion measurements of anisotropic fluids, and of fluids restricted by walls of microfluidic channels. For the latter, the free diffusion and the localisation regime are considered. Published by AIP Publishing.Armata F , Vasile R , Barcellona P , Buhmann S , Rizzuto L , Passante R Dynamical Casimir-Polder force between an excited atom and a conducting wall 2016 PHYSICAL REVIEW A , Band : 94, Nummer : 4Barcellona P , Passante R , Rizzuto L , Buhmann S Dynamical Casimir-Polder interaction between a chiral molecule and a surface 2016 PHYSICAL REVIEW A , Band : 93, Nummer : 3» Kurzfassung anzeigen « Kurzfassung verbergen Kurzfassung We develop a dynamical approach to study the Casimir-Polder force between an initially bare molecule and a magnetodielectric body at finite temperature, valid for arbitrary magnetodielectric properties and also in the presence of chiral effects. Switching on the interaction between the molecule and the field at a particular time, we study the resulting temporal evolution of the Casimir-Polder interaction. The dynamical self-dressing of the molecule and its population-induced dynamics are accounted for and discussed. In particular, we find that the Casimir-Polder force between a molecule and a surface oscillates in time with a frequency related to the molecular transition frequency. We verify that the dynamical force converges to the static result for time much larger than the inverse of the transition frequency, and it is particularly strong around the back-reaction time t = 2d/c, the time needed for the molecule to emit and reabsorb a photon reflected by the surface.Thorwart M Dynamics of a quantum two-state system in a linearly driven quantum bath 2016 Phys Rev A Reichert J , Nalbach P , Thorwart M Dynamics of a quantum two-state system in a linearly driven quantum bath 2016 PHYSICAL REVIEW A , Band : 94, Nummer : 3Taheri H , Samyn P Effect of homogenization (microfluidization) process parameters in mechanical production of micro- and nanofibrillated cellulose on its rheological and morphological properties 2016 CELLULOSE , Band : 23, Nummer : 2, Seiten : 1221 - 1238» Kurzfassung anzeigen « Kurzfassung verbergen Kurzfassung The rheological properties of microfibrillated cellulose (MFC)/nanofibrillated cellulose (NFC) suspensions have an important role during processing and mixing. In this work, the process parameters for MFC/NFC production within a microfluidizer (i.e., the size of interaction chamber and number of passes) were varied to investigate the influences on morphology, zeta potential, chemical properties and rheological features including viscosity, creep, strain recovery and yield stress behavior. The stability and appropriate viscosity of the fiber suspensions can be controlled by optimizing the processing conditions, resulting in a reduction in fiber diameter and most negative zeta potential value. The viscosity increased with higher amount of fibrillation by using a smaller chamber or higher number of passes, but intermediate plateau values are characteristic for temporary aggregation and breaking-up of the fiber network. The creep response and yield stress have been described by parameters of the Burger model and Herschel-Bulkley model, respectively, showing a more prominent effect on yield stress of chamber size than number of passes. The network formation leads to lower creep compliance and step-like strain recovery. The transition from gel-like to liquid-like behavior as characterized by the dynamic yield point at a specific strain, is almost independent of the processing conditions. Most important, the total number of passes applied in production can be directly related to the rotational P,clet number, which combines rheological and morphological data.Kropf C , Gneiting C , Buchleitner A Effective Dynamics of Disordered Quantum Systems 2016 PHYSICAL REVIEW X , Band : 6, Nummer : 3Thiyam P , Lima E , Malyi O , Parsons D , Buhmann S , Persson C , Bostrom M Effects of van der Waals forces and salt ions on the growth of water films on ice and the detachment of CO2 bubbles 2016 EPL , Band : 113, Nummer : 4» Kurzfassung anzeigen « Kurzfassung verbergen Kurzfassung We study the effect of salts on the thickness of wetting films on melting ice and interactions acting on CO2 bubble near ice-water and vapor-water interfaces. Governing mechanisms are the Lifshitz and the double-layer interactions in the respective three-layer geometries. We demonstrate that the latter depend on the Casimir-Polder interaction of the salt ions dissolved in water with the respective ice, vapor and CO2 interfaces, as calculated using different models for their effective polarizability in water. Significant variation in the predicted thickness of the equilibrium water film is observed for different salt ions and when using different models for the ions’ polarizabilities. We find that CO2 bubbles are attracted towards the ice-water interface and repelled from the vapor-water interface. Copyright (C) EPLA, 2016Yerokhin V , Buhmann S , Fritzsche S , Surzhykov A Electric dipole polarizabilities of Rydberg states of alkali-metal atoms 2016 PHYSICAL REVIEW A , Band : 94, Nummer : 3Kandrashkin Y , Poddutoori P , van der Est A Electron Transfer Pathways in a Tetrathiafulvalene-Aluminum(III) Porphyrin-Free-Base Porphyrin Triad Studied Using Electron Spin Polarization 2016 APPLIED MAGNETIC RESONANCE , Band : 47, Nummer : 5, Seiten : 511 - 526» Kurzfassung anzeigen « Kurzfassung verbergen Kurzfassung The electron transfer pathways in two axially bound triads based on aluminum(III) porphyrin (AlPor) are investigated using the electron spin polarization patterns of the final radical pair state. In the triads, TTF-(Ph)(n)-py-AlPor-Ph-H(2)Por (n = 0, 1), free-base porphyrin (H(2)Por) is attached covalently to the Al(III) center, while the donor tetrathiafulvalene (TTF) coordinates to Al(III) via an appended pyridine on the opposite face of the porphyrin ring. Excitation of the triad at 532 nm leads to absorption by both AlPor and H(2)Por and to two possible charge separation pathways. In the liquid crystalline solvent 5CB, spin polarized transient electron paramagnetic resonance spectra of a weakly coupled radical pair are observed and assigned to the state . The radical pair spectra are analyzed using a structural model of the complex to determine the dipolar coupling and relative orientation of the radicals. The inertia tensor calculated from the structural model is used to derive the principal values and axes of the order matrix. It is shown that the observed polarization pattern is only consistent with ferromagnetic exchange coupling in the radical pair. The spectra can be reproduced as the sum of two contributions originating in electron transfer from the excited singlet state of AlPor and from the excited the triplet state of H(2)Por. The latter is shown to account for the integral emissive net polarization observed in the spectra.Antonioli M , Di Rienzo M , Piacentini M , Fimia GM Emerging Mechanisms in Initiating and Terminating Autophagy. 2016 Trends Biochem Sci Ganss S , Breit B Enantioselective Rhodium-Catalyzed Atom-Economical Macrolactonization 2016 Angew Chem Int Edit , Band : 55, Seiten : 9738 - 9742Omairi S , Matsakas A , ... , Huber T , Patel K Enhanced exercise and regenerative capacity in a mouse model that violates size constraints of oxidative muscle fibres 2016 ELIFE , Band : 5Schiffmann I , Greve G , Jung M , Luebbert M Epigenetic therapy approaches in non-small cell lung cancer: Update and perspectives 2016 EPIGENETICS , Band : 11, Nummer : 12, Seiten : 858 - 870Mendoza-Coto A , Diaz-Mendez R , Pupillo G Event-driven Monte Carlo: Exact dynamics at all time scales for discrete-variable models 2016 EPL , Band : 114, Nummer : 5» Kurzfassung anzeigen « Kurzfassung verbergen Kurzfassung We present an algorithm for the simulation of the exact real-time dynamics of classical many-body systems with discrete energy levels. In the same spirit of kinetic Monte Carlo methods, a stochastic solution of the master equation is found, with no need to define any other phase-space construction. However, unlike existing methods, the present algorithm does not assume any particular statistical distribution to perform moves or to advance the time, and thus is a unique tool for the numerical exploration of fast and ultra-fast dynamical regimes. By decomposing the problem in a set of two-level subsystems, we find a natural variable step size, that is well defined from the normalization condition of the transition probabilities between the levels. We successfully test the algorithm with known exact solutions for non-equilibrium dynamics and equilibrium thermodynamical properties of Ising-spin models in one and two dimensions, and compare to standard implementations of kinetic Monte Carlo methods. The present algorithm is directly applicable to the study of the real-time dynamics of a large class of classical Markovian chains, and particularly to short-time situations where the exact evolution is relevant. Copyright (C) EPLA, 2016Liu Z , Tavares R , Forsythe ES , Andre F , Lugan R , Jonasson G , Boutet-Mercey S , Tohge T , Beilstein MA , Werck-Reichhart D , Renault H Evolutionary interplay between sister cytochrome P450 genes shapes plasticity in plant metabolism. 2016 Nat Commun , Band : 7, Seiten : 13026 - 13026Zarei M , Sprenger A , Rackiewicz M , Dengjel J Fast and easy phosphopeptide fractionation by combinatorial ERLIC-SCX solid-phase extraction for in-depth phosphoproteome analysis. 2016 Nat Protoc , Band : 11, Nummer : 1, Seiten : 37 - 45Nazio F , ... , Antonioli M , ... , Cecconi F Fine-tuning of ULK1 mRNA and protein levels is required for autophagy oscillation. 2016 J Cell Biol , Band : 215, Nummer : 6, Seiten : 841 - 856Campana F Fundamental group and pluridifferentials on compact Kähler manifolds 2016 Mosc Math J , Band : 16, Nummer : 4, Seiten : 651 - 658Carnio E , Buchleitner A , Gessner M Generating and protecting correlated quantum states under collective dephasing 2016 NEW JOURNAL OF PHYSICS , Band : 18Kebekus S Generic positivity and applications to hyperbolicity of moduli spaces 2016 J Algebraic Geom Klionsky DJ , Abeliovich H , Dengjel J , et.al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). 2016 Autophagy , Band : 12, Nummer : 1, Seiten : 1 - 222Pham T , Schreiber A , Sturm E , Schiller S , Coelfen H Hemolysin coregulated protein 1 as a molecular gluing unit for the assembly of nanoparticle hybrid structures 2016 BEILSTEIN JOURNAL OF NANOTECHNOLOGY , Band : 7, Seiten : 351 - 363Spengler N , Hofflin J , Moazenzadeh A , Mager D , MacKinnon N , Badilita V , Wallrabe U , Korvink JG Heteronuclear Micro-Helmholtz Coil Facilitates microm-Range Spatial and Sub-Hz Spectral Resolution NMR of nL-Volume Samples on Customisable Microfluidic Chips. 2016 Plos One , Band : 11, Nummer : 1, Seiten : e0146384 - e0146384Haddadfarshi F , Mintert F High fidelity quantum gates of trapped ions in the presence of motional heating 2016 NEW JOURNAL OF PHYSICS , Band : 18Tharaux PL , Huber TB How Is Proteinuric Diabetic Nephropathy Caused by Disturbed Proteostasis and Autophagy in Podocytes? 2016 Diabetes , Band : 65, Nummer : 3, Seiten : 539 - 541Carranza A , Singh A , Steinberger K , Panigrahi K , Palme K , Dovzhenko A , Dal Bosco C Hydrolases of the ILR1-like family of Arabidopsis thaliana modulate auxin response by regulating auxin homeostasis in the endoplasmic reticulum 2016 SCIENTIFIC REPORTS , Band : 6» Kurzfassung anzeigen « Kurzfassung verbergen Kurzfassung Amide-linked conjugates of indole-3-acetic acid (IAA) have been identified in most plant species. They function in storage, inactivation or inhibition of the growth regulator auxin. We investigated how the major known endogenous amide-linked IAA conjugates with auxin-like activity act in auxin signaling and what role ILR1-like proteins play in this process in Arabidopsis. We used a genetically encoded auxin sensor to show that IAA-Leu, IAA-Ala and IAA-Phe act through the TIR1-dependent signaling pathway. Furthermore, by using the sensor as a free IAA reporter, we followed conjugate hydrolysis mediated by ILR1, ILL2 and IAR3 in plant cells and correlated the activity of the hydrolases with a modulation of auxin response. The conjugate preferences that we observed are in agreement with available in vitro data for ILR1. Moreover, we identified IAA-Leu as an additional substrate for IAR3 and showed that ILL2 has a more moderate kinetic performance than observed in vitro. Finally, we proved that IAR3, ILL2 and ILR1 reside in the endoplasmic reticulum, indicating that in this compartment the hydrolases regulate the rates of amido-IAA hydrolysis which results in activation of auxin signaling.Robaa D , Wagner T , Luise C , Carlino L , McMillan J , Flaig R , Schüle R , Jung M , Sippl W Identification and Structure–Activity Relationship Studies of Small‐Molecule Inhibitors of the Methyllysine Reader Protein Spindlin1 2016 Chemmedchem , Band : 11, Nummer : 20, Seiten : 2327 - 2338Slynko I , ... , Schüle R , Jung M , Sippl W Identification of Highly Potent Protein Kinase C‐Related Kinase 1 Inhibitors by Virtual Screening, Binding Free Energy Rescoring, and in vitro Testing 2016 Chemmedchem , Band : 11, Nummer : 18, Seiten : 2084 - 2094Hoernstein SN , Mueller SJ , ... , Schlosser A , Reski R Identification of Targets and Interaction Partners of Arginyl-tRNA Protein Transferase in the Moss Physcomitrella patens. 2016 Mol Cell Proteomics , Band : 15, Nummer : 6, Seiten : 1808 - 1822Wagner T , Greschik H , Burgahn T , Schmidtkunz K , Schott AK , McMillan J , Baranauskienė L , Xiong Y , Fedorov O , Jin J , Oppermann U , Matulis D , Schüle R , Jung M Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform 2016 Nucl. Acids Res. Hemmerich J , Bennett R , Reisinger T , Nimmrichter S , Fiedler J , Hahn H , Gleiter H , Buhmann S Impact of Casimir-Polder interaction on Poisson-spot diffraction at a dielectric sphere 2016 PHYSICAL REVIEW A , Band : 94, Nummer : 2Buhmann S , Marachevsky V , Scheel S Impact of anisotropy on the interaction of an atom with a one-dimensional nano-grating 2016 INTERNATIONAL JOURNAL OF MODERN PHYSICS A , Band : 31, Nummer : 2-3, SI» Kurzfassung anzeigen « Kurzfassung verbergen Kurzfassung We study the interaction of an atom with a one-dimensional nano-grating within the framework of macroscopic QED, with special emphasis on possible anisotropic contributions. To this end, we first derive the scattering Green’s tensor of the grating by means of a Rayleigh expansion and discuss its symmetry properties and asymptotes. We then determine the Casimir-Polder potential of an atom with the grating. In particular, we find that strong anisotropy can lead to a repulsive Casimir-Polder potential in the normal direction.Rosales-Mendoza S , Salazar-Gonzalez JA , Decker EL , Reski R Implications of plant glycans in the development of innovative vaccines. 2016 Expert Rev Vaccines , Band : 15, Nummer : 7, Seiten : 915 - 925Simon R , Robaa D , Alhalabi Z , Sippl W , Jung M KATching-Up on Small Molecule Modulators of Lysine Acetyltransferases 2016 JOURNAL OF MEDICINAL CHEMISTRY , Band : 59, Nummer : 4, SI, Seiten : 1249 - 1270Brenker K , Osthof K , Yang J , Reth M LED Thermo Flow - Combining Optogenetics with Flow Cytometry. 2016 Jove-j Vis Exp , Nummer : 118Oliveira A , Ordonez JS , Vajari DA , Eickenscheidt M , Stieglitz T Laser-Induced Carbon Pyrolysis of Electrodes for Neural Interface Systems. 2016 Eur J Transl Myol , Band : 26, Nummer : 3, Seiten : 6062 - 6062Svagan AJ , Bender Koch C , Hedenqvist MS , Nilsson F , Glasser G , Baluschev S , Andersen ML Liquid-core nanocellulose-shell capsules with tunable oxygen permeability. 2016 Carbohyd Polym , Band : 136, Seiten : 292 - 299Pedigo C , Ducasa G , ... , Huber T , Mendez A , Merscher S , Fornoni A Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury 2016 JOURNAL OF CLINICAL INVESTIGATION , Band : 126, Nummer : 9, Seiten : 3336 - 3350Fritzewski DJ , ... , Raetz S , ... , Wolf V Long-term photometry of IC 348 with the Young Exoplanet Transit Initiative network 2016 Mon Not R Astron Soc , Band : 432Goussev A , Jalabert R , Pastawski HM , Wisniacki DA Loschmidt echo and time reversal in complex systems 2016 Phil. Trans. R. Soc. A , Band : 374Czulkies BA , Mastroianni J , ... , Aktories K , Papatheodorou P Loss of LSR affects epithelial barrier integrity and tumor xenograft growth of 2016 Oncotarget Ni J , Bao S , Johnson RI , Zhu B , Li J , Vadaparampil J , Smith CM , Campbell KN , Grahammer F , Huber TB , He JC , D'Agati VD , Chan A , Kaufman L MAGI-1 Interacts with Nephrin to Maintain Slit Diaphragm Structure through Enhanced Rap1 Activation in Podocytes. 2016 J Biol Chem , Band : 291, Nummer : 47, Seiten : 24406 - 24417Carmen Moron M , Prada-Gracia D , Falo F Macro and nano scale modelling of water-water interactions at ambient and low temperature: relaxation and residence times 2016 PHYSICAL CHEMISTRY CHEMICAL PHYSICS , Band : 18, Nummer : 14, Seiten : 9377 - 9387» Kurzfassung anzeigen « Kurzfassung verbergen Kurzfassung The decay dynamics of ambient and low temperature liquid water has been investigated through all-atom molecular dynamics simulations, residence times calculations and time correlation functions from 300 K down to 243 K. Those simulations replicate the experimental value of the self-diffusion constant as a function of temperature by tuning the damping factor of the Langevin equation of motion. A stretched exponential function exp[-(t/tau)(beta)] has been found to properly describe the relaxation of residence times calculated at different temperatures for solvent molecules in a nanodrop of free water modelled as a sphere of nanometric dimensions. As the temperature goes down the decay time tau increases showing a divergence at T-s = 227 +/- 3 K. The temperature independence of the dimensionless stretched exponent beta = 0.59 +/- 0.01 suggests the presence of, not a characteristic relaxation time (since beta not equal 1), but a distribution of decay times that also holds at low temperature. An explanation for such heterogeneity can be found at the nanoscopic level. Moreover it can be concluded that the distribution of times already reported for the dynamics of water surrounding proteins (beta <= 0.5) can not be exclusively due to the presence of the biomolecule itself since isolated water also exhibits such behaviour. The above reported Ts and b values quantitatively reproduce experimental data.Loi M , ... , Dengjel J , Garcia-Sastre A , Merkler D , Munz C , Gannage M Macroautophagy Proteins Control MHC Class I Levels on Dendritic Cells and Shape 2016 Cell Rep , Band : 15, Nummer : 5, Seiten : 1076 - 1087Spiegelhalder K , Regen W , Nissen C , Feige B , Baglioni C , Riemann D , Hennig J , Lange T Magnetic Resonance Spectroscopy in Patients with Insomnia: A Repeated Measurement Study. 2016 Plos One , Band : 11, Nummer : 6, Seiten : e0156771 - e0156771Shklyarov D Matrix factorizations and higher residue pairings 2016 Advances in Mathematics , Band : 292, Seiten : 181 - 209Lauks J , Mramor B , Baumgartl K , Maier H , Nickel CH , Bingisser R Medical Team Evaluation: Effect on Emergency Department Waiting Time and Length of Stay. 2016 Plos One , Band : 11, Nummer : 4, Seiten : e0154372 - e0154372Jalabert R Mesoscopic transport and quantum chaos 2016 Scholarpedia , Band : 11, Nummer : 1Pan D , ... , Jung M , Gunther S , Kammerer B Metabolic Response to XD14 Treatment in Human Breast Cancer Cell Line MCF-7 2016 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , Band : 17, Nummer : 10Gonzalez AG , Pokrovsky OS , Beike AK , Reski R , Di Palma A , Adamo P , Giordano S , Fernandez JA Metal and proton adsorption capacities of natural and cloned Sphagnum mosses. 2016 J Colloid Interf Sci , Band : 461, Seiten : 326 - 334Campana F Mihai Positivity properties of the bundle of logarithmic tensors on compact Kähler manifolds 2016 Compos Math , Band : 152, Nummer : 11, Seiten : 2350 - 2370Rao A , Colfen H Mineralization and non-ideality: on nature's foundry. 2016 Biophys Rev , Band : 8, Nummer : 4, Seiten : 309 - 329Abeliovich H , Dengjel J Mitophagy as a stress response in mammalian cells and in respiring S. cerevisiae. 2016 Biochem Soc T , Band : 44, Nummer : 2, Seiten : 541 - 545Obondi C , Lim GN , ... , van der Est A , D'Souza F Modulating the generation of long-lived charge separated states exclusively from the triplet excited states in palladium porphyrin-fullerene conjugates. 2016 Nanoscale , Band : 8, Nummer : 15, Seiten : 8333 - 8344Di Palma A , ... , Reski R , Tretiach M , Varela Z , Giordano S Molecular and chemical characterization of a Sphagnum palustre clone: Key steps towards a standardized and sustainable moss bag technique 2016 ECOLOGICAL INDICATORS , Band : 71, Seiten : 388 - 397Volkmann C , Brings N , Becker M , Hobeika E , Yang J , Reth M Molecular requirements of the B-cell antigen receptor for sensing monovalent antigens. 2016 Embo J , Band : 35, Nummer : 21, Seiten : 2371 - 2381Michelfelder S , ... , Reski R , Decker EL , Häffner K Moss-Produced, Glycosylation-Optimized Human
Factor H for Therapeutic Application in Complement
Disorders 2016 J Am Soc Nephrol , Band : 28Bennett K , Zhang Y , Kowalewski M , Hua W , Mukamel S Multidimensional resonant nonlinear spectroscopy with coherent broadband x-ray pulses 2016 PHYSICA SCRIPTA , Band : T169Bae J , Hwang WY , Su HY N-dimensional measurement device independent QKD with N+1 uncharacterized sources 2016 Sci Rep-uk , Band : 30036Neto S , Varatharajan R , Joseph K , Moser A Nasal administration of leptin dose-dependently increases dopamine and serotonin outflow in the rat nucleus accumbens. 2016 J Neural Transm , Band : 123, Nummer : 11, Seiten : 1247 - 1254Rassner MP , Moser A , Follo M , Joseph K , van Velthoven-Wurster V , Feuerstein TJ Neocortical GABA release at high intracellular sodium and low extracellular calcium: an anti-seizure mechanism. 2016 J Neurochem , Band : 137, Nummer : 2, Seiten : 177 - 189Grabert H , Nalbach P , Reichert J , Thorwart M Nonequilibrium Response of Nanosystems Coupled to Driven Quantum Baths 2016 JOURNAL OF PHYSICAL CHEMISTRY LETTERS , Band : 7, Nummer : 11, Seiten : 2015 - 2019Grabert H , Nalbach P , Reichert J , Thorwart M Nonequilibrium Response of Nanosystems Coupled to Driven Quantum Baths. 2016 J Phys Chem Lett , Band : 7, Nummer : 11, Seiten : 2015 - 2019Spiegelhalder K Objective sleep disturbances are associated with greater waking resting-state connectivity between the retrosplenial cortex/ hippocampus and various nodes of the default mode network 2016 J Psychiatr Neurosci , Band : 41, Seiten : 295 - 303Abeliovich H On Hill coefficients and subunit interaction energies. 2016 J Math Biol Shklyarov D On a Hodge theoretic property of the Kunneth map in periodic cyclic homology 2016 JOURNAL OF ALGEBRA , Band : 446, Seiten : 132 - 153» Kurzfassung anzeigen « Kurzfassung verbergen Kurzfassung We prove that the standard Kunneth map in periodic cyclic homology of differential Z/2-graded algebras is compatible with a generalization of the Hodge filtration and explain how this result is related to various Thom-Sebastiani type theorems in singularity theory. (C) 2015 Elsevier Inc. All rights reserved.Bae J , Chruscinski D Operational Characterization of Divisibility of Dynamical Maps. 2016 Phys Rev Lett , Band : 117, Nummer : 5, Seiten : 050403 - 050403Laird BB Orientation dependence of heterogeneous nucleation at the Cu-Pb solid-liquid interface 2016 J Chem Phys , Band : 45, Nummer : 211914, Seiten : 1 - 12Chater CC , ... , Fleming A , Reski R , Beerling DJ Origin and function of stomata in the moss Physcomitrella patens 2016 Nat Plants , Band : 2, Seite : 16179Zeuner MT , Patel K , Denecke B , Giebel B , Widera D Paracrine effects of TLR4-polarised mesenchymal stromal cells are mediated by extracellular vesicles. 2016 J Transl Med , Band : 14, Seiten : 34 - 34Brindisi M , ... , Jung M , Campiani G , Gemma S Phenylpyrrole-based HDAC inhibitors: synthesis, molecular modeling and biological studies 2016 Future Med Chem , Band : 8, Seiten : 1573 - 1587Eisenhardt AE , Sprenger A , ... , Baumeister R , Schlosser A , Dengjel J , Brummer T Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles. 2016 Oncotarget Li Y , Majarian TD , Naik AW , Johnson GR , Murphy RF Point process models for localization and interdependence of punctate cellular structures. 2016 Cytom Part A , Band : 89, Nummer : 7, Seiten : 633 - 643Hügle M , Lucas X , Weitzel G , Ostrovskyi D , Breit B , Gerhard S , Schmidtkunz K , Jung M , Schüle R , Einsle O , Günther S , Wohlwend D Preparation data of the bromodomains BRD3(1), BRD3(2), BRD4(1), and BRPF1B and crystallization of BRD4(1)-inhibitor complexes 2016 Data Brief , Band : 7, Seiten : 1370 - 1374Baluschev S Protection of densely populated excited triplet state ensembles against deactivation by molecular oxygen 2016 Chem Soc Rev , Band : 136, Seiten : 292 - 299Halbach S , Dengjel J , Brummer T Quantitative Proteomics Analysis of Leukemia Cells. 2016 Methods Mol Biol , Band : 1465, Seiten : 139 - 148Walschaers M , Schlawin F , Wellens T , Buchleitner A Quantum Transport on Disordered and Noisy Networks: An Interplay of Structural Complexity and Uncertainty 2016 ANNUAL REVIEW OF CONDENSED MATTER PHYSICS, VOL 7 , Band : 7, Seiten : 223 - 248» Kurzfassung anzeigen « Kurzfassung verbergen Kurzfassung We discuss recent research on quantum transport in complex materials, from photosynthetic light-harvesting complexes to photonic circuits. We identify finite, disordered networks as the underlying backbone and as a versatile framework to gain insight into the specific potential of nontrivial quantum dynamical effects to characterize and control transport on complex structures. We discriminate authentic quantum properties from classical aspects of complexity and briefly address the impact of interactions, nonlinearities, and noise. We stress the relevance of what we call the nonasymptotic realm, physical situations in which neither the relevant time-and length-scales, the number of degrees of freedom, or constituents tend to very small or very large values, nor do global symmetries or disorder fully govern the dynamics. Although largely uncharted territory, we argue that novel, intriguing and nontrivial questions for experimental and theoretical work emerge, with the prospect of a unified understanding of complex quantum transport phenomena in diverse physical settings.Bermudez A , Schaetz T Quantum transport of energy in controlled synthetic quantum magnets 2016 NEW JOURNAL OF PHYSICS , Band : 18Verdeny A , Puig J , Mintert F Quasi-Periodically Driven Quantum Systems 2016 ZEITSCHRIFT FUR NATURFORSCHUNG SECTION A-A JOURNAL OF PHYSICAL SCIENCES , Band : 71, Nummer : 10, Seiten : 897 - 907Campana F Rational connectedness and order of non-degenerate meromorphic maps from Cn 2016 Eur. J. Math. , Band : 2, Nummer : 1, Seiten : 87 - 95Rastogi VK , Stanssens D , Samyn P Reaction efficiency and retention of poly(styrene-co-maleimide) nanoparticles deposited on fibrillated cellulose surfaces. 2016 Carbohyd Polym , Band : 141, Seiten : 244 - 252Yang J , Reth M Receptor Dissociation and B-Cell Activation. 2016 Curr Top Microbiol , Band : 393, Seiten : 27 - 43Haydl AM , Hilpert LJ , Breit B Regioconvergent and Enantioselective Rhodium-Catalyzed Hydroamination of Internal and Terminal Alkynes: A Highly Flexible Access to Chiral Pyrazoles 2016 Chem. Eur. J. , Band : 22, Seiten : 6547 - 6551Beck TM , Breit B Regioselective Rhodium-Catalyzed Addition of 1,3-Dicarbonyl Compounds to Terminal Alkynes 2016 Org Lett , Band : 18, Seiten : 124 - 127Beck TM , Breit B Regioselective Rhodium-Catalyzed Addition of β-Keto Esters, β-Keto Amides and 1,3-Diketones to Internal Alkynes 2016 Eur J Org Chem , Band : 93, Seiten : 5839 - 5844Taheri H , Stanssens D , Samyn P Rheological behaviour of oil-filled polymer nanoparticles in aqueous dispersion 2016 COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS , Band : 499, Seiten : 31 - 45» Kurzfassung anzeigen « Kurzfassung verbergen Kurzfassung Hybrid organic nanoparticles of poly(styrene-co-maleimide) with 70 wt.-% incorporated palm oil (SMI/oil) were provided in aqueous dispersion for use in industrial coating processes. The rheological characteristics of dispersions with 65 wt.-% and 35 wt.-% solid content have been determined by creep, oscillatory and rotational testing under different shear stresses, shear rates, frequencies and temperatures. The effects of oil on viscoelastic properties have been demonstrated by comparative tests on a 35 wt.-% pure SMI nanoparticle dispersion. The creep and strain recovery data show viscoelastic responses only for 65 wt.-% SMI/oil dispersions at low stresses, as further detailed by the calculated Burger model parameters. The 65 wt.-% SMI/oil dispersion at higher stresses and 35 wt.-% SMI/oil dispersion over the full stress range become viscous. From strain sweep tests, the cross-over of G’ and G” demonstrates linear features at low strain and a transition into viscoelastic properties at high strain. The frequency sweep test indicates a linear solid-like behaviour with storage and loss modulus independent of frequencies at temperatures up to 70 degrees C. From rotational tests, the sensitivity of shear-viscosity properties to concentration and temperature has been demonstrated. The oscillatory and rotational data can be fitted by the Cox-Merz rule using dynamic viscosity and shear viscosity as a function of frequency or shear stress, while a yield point has been detected as a function of shear stress for both 65 and 35 wt.-% SMI/oil dispersions. (C) 2016 Elsevier B.V. All rights reserved.Samyn P , Taheri H Rheology of fibrillated cellulose suspensions after surface modification by organic nanoparticle deposits 2016 JOURNAL OF MATERIALS SCIENCE , Band : 51, Nummer : 21, Seiten : 9830 - 9848Jank T , Lang A , Aktories K Rho-modifying bacterial protein toxins from Photorhabdus species 2016 TOXICON , Band : 116, Nummer : SI, Seiten : 17 - 22Ganss S , Pedroni J , Lumbroso A , Leonhardt-Lutterbeck G , Meißner A , Wei S , Drexler HJ , Heller D , Breit B Rhodium-Catalyzed Addition of Carboxylic Acids to Terminal Alkynes towards Z-Enol Esters 2016 Org. Synth. , Band : 93, Seiten : 367 - 384Spreider P , Haydl A , Heinrich M , Breit B Rhodium-Catalyzed Diastereoselective Cyclization of Allenylsulfonylcarbamates: A Stereodivergent Approach to 1,3-Aminoalcohol Derivatives 2016 Angew Chem Int Edit , Band : 55, Seiten : 15569 - 15573Li C , Breit B Rhodium-Catalyzed Dynamic Kinetic Asymmetric Allylation of Phenols and 2-Hydroxypyridines 2016 Chem. Eur. J. , Band : 22, Seiten : 14655 - 14663Liu Z , Breit B Rhodium-Catalyzed Enantioselective Intermolecular Hydroalkoxylation of Allenes and Alkynes with Alcohols Leading to Branched Allylic Ethers 2016 Angew Chem Int Edit , Band : 55, Seiten : 8440 - 8443Li C , Grugel CP , Breit B Rhodium-catalyzed chemo- and regioselective decarboxylative addition of β-ketoacids to alkynes 2016 Chem Commun , Band : 52, Seiten : 5840 - 5843Dengjel J , Abeliovich H Roles of mitophagy in cellular physiology and development. 2016 Cell Tissue Res Buchenberg S , Leitner DM , Stock G Scaling Rules for Vibrational Energy Transport in Globular Proteins. 2016 J Phys Chem Lett , Band : 7, Nummer : 1, Seiten : 25 - 30Jalabert R , Weinmann D Scattering approach to scanning gate microscopy (Reprinted) 2016 PHYSICA E-LOW-DIMENSIONAL SYSTEMS & NANOSTRUCTURES , Band : 82, Seiten : 286 - 292» Kurzfassung anzeigen « Kurzfassung verbergen Kurzfassung We present a perturbative approach to the conductance change caused by a weakly invasive scattering potential in a two-dimensional electron gas. The resulting expressions are used to investigate the relationship between the conductance change measured in scanning gate microscopy as a function of the position of a scattering tip and local electronic quantities like the current density. We use a semiclassical approach to treat the case of a strong hard-wall scatterer in a half-plane facing a reflectionless channel. The resulting conductance change is consistent with the numerically calculated quantum conductance. (C) 2016 Published by Elsevier B.V.Nolke T , Schwan C , Lehmann F , Ostevold K , Pertz O , Aktories K Septins guide microtubule protrusions induced by actin-depolymerizing toxins like Clostridium difficile transferase (CDT). 2016 P Natl Acad Sci Usa , Band : 113, Nummer : 28, Seiten : 7870 - 7875Maier K , He Y , Esser P , Thriene K , Sarca D , Kohlhase J , Dengjel J , Martin L , Has C Single amino acid deletion in kindlin-1 results in partial protein degradation which can be rescued by chaperone treatment 2016 EXPERIMENTAL DERMATOLOGY , Band : 25, Nummer : 3Zhang D , Shao Z , Yan W , Li An , Skourtis S Size-Selective Kinetics of Nanostructured Pt/GC Model Electrocatalysts for CO Stripping 2016 JOURNAL OF PHYSICAL CHEMISTRY C , Band : 120, Nummer : 11, Seiten : 6218 - 6224Alicki R , Gelbwaser-Klimovsky D , Szczygielski K Solar cell as a self-oscillating heat engine 2016 JOURNAL OF PHYSICS A-MATHEMATICAL AND THEORETICAL , Band : 49, Nummer : 1Schuessele C , Hoernstein SN , Mueller SJ , Rodriguez-Franco M , Lorenz T , Lang D , Igloi GL , Reski R Spatio-temporal patterning of arginyl-tRNA protein transferase (ATE) contributes to gametophytic development in a moss. 2016 New Phytol , Band : 209, Nummer : 3, Seiten : 1014 - 1027Samyn P , Van Erps J , Thienpont H Specular gloss versus surface topography for oil-filled nanoparticle coatings on paper 2016 COLOR RESEARCH AND APPLICATION , Band : 41, Nummer : 6, Seiten : 596 - 610Corlatti L , Gugiatti A , Pedrotti L Spring spotlight counts provide reliable indices to track changes in population size of mountain-dwelling red deer Cervus elaphus 2016 WILDLIFE BIOLOGY , Band : 22, Nummer : 6, Seiten : 268 - 276Haydl AM , Berthold D , Spreider PA , Breit B Stereodivergent and Protecting-Group-Free Synthesis of the Helicascolide Family: A Rhodium-Catalyzed Atom-Economical Lactonization Strategy 2016 Angew. Chem. , Band : 128, Seiten : 5859 - 5863Sibout R , Le Bris P , Legee F , Cezard L , Renault H , Lapierre C Structural Redesigning Arabidopsis Lignins into Alkali-Soluble Lignins through the Expression of p-Coumaroyl-CoA: Monolignol Transferase PMT 2016 PLANT PHYSIOLOGY , Band : 170, Nummer : 3, Seiten : 1358 - 1366» Kurzfassung anzeigen « Kurzfassung verbergen Kurzfassung Grass lignins can contain up to 10% to 15% by weight of p-coumaric esters. This acylation is performed on monolignols under the catalysis of p-coumaroyl-coenzyme A monolignol transferase (PMT). To study the impact of p-coumaroylation on lignification, we first introduced the Brachypodium distachyon Bradi2g36910 (BdPMT1) gene into Arabidopsis (Arabidopsis thaliana) under the control of the constitutive maize (Zea mays) ubiquitin promoter. The resulting p-coumaroylation was far lower than that of lignins from mature grass stems and had no impact on stem lignin content. By contrast, introducing either the BdPMT1 or the Bradi1g36980 (BdPMT2) gene into Arabidopsis under the control of the Arabidopsis cinnamate-4-hydroxylase promoter boosted the p-coumaroylation of mature stems up to the grass lignin level (8% to 9% by weight), without any impact on plant development. The analysis of purified lignin fractions and the identification of diagnostic products confirmed that p-coumaric acid was associated with lignins. BdPMT1-driven p-coumaroylation was also obtained in the fah1 (deficient for ferulate 5-hydroxylase) and ccr1g (deficient for cinnamoyl-coenzyme A reductase) lines, albeit to a lower extent. Lignins from BdPMT1-expressing ccr1g lines were also found to be feruloylated. In Arabidopsis mature stems, substantial p-coumaroylation of lignins was achieved at the expense of lignin content and induced lignin structural alterations, with an unexpected increase of lignin units with free phenolic groups. This higher frequency of free phenolic groups in Arabidopsis lignins doubled their solubility in alkali at room temperature. These findings suggest that the formation of alkali-leachable lignin domains rich in free phenolic groups is favored when p-coumaroylated monolignols participate in lignification in a grass in a similar manner.Heimburg T , Chakrabarti A , ... , Pierce RJ , Jung M , Sippl W Structure-based design and synthesis of novel inhibitors targeting HDAC8 from Schistosoma mansoni for the treatment of schistosomiasis 2016 J Med Chem , Band : 59, Seiten : 2423 - 2435Schiedel M , Rumpf T , Karaman B , Lehotzky A , Gerhardt S , Ovádi J , Sippl W , Einsle O , Jung M Structure-based development of a Sirtuin 2 affinity probe 2016 Angew Chem Int Edit , Band : 55, Seiten : 2252 - 2256Roatsch M , Robaa D , Pippel M , Nettleship JE , Reddivari Y , Bird LE , Hoffmann I , Franz H , Owens RJ , Schüle R , Flaig R , Sippl W , Jung M Substituted 2-(2-aminopyrimidin-4-yl)pyridine-4-carboxylates as potent inhibitors of JumonjiC domain-containing histone demethylases 2016 Future Med Chem , Band : 8, Seiten : 1553 - 1571Green KA , Becker Y , Tanaka A , Takemoto D , Fitzsimons HL , Seiler S , Lalucque H , Silar P , Scott B SymB and SymC, two membrane associated proteins, are required for Epichloe festucae hyphal cell-cell fusion and maintenance of a mutualistic interaction with Lolium perenne. 2016 Mol Microbiol Senger J , Melesina J , Marek M , Romier C , Oehme I , Witt O , Sippl W , Jung M Synthesis and biological investigation of oxazole hydroxamates as highly selective histone deacetylase 6 (HDAC6) inhibitors 2016 J Med Chem , Band : 59, Seiten : 1545 - 1555Jiang L , Papageorgiou A , ... , More S , Bhosale R , Mateo-Alonso A , Barth JV Synthesis of Pyrene-Fused Pyrazaacenes on Metal Surfaces: Toward One-Dimensional Conjugated Nanostructures 2016 ACS NANO , Band : 10, Nummer : 1, Seiten : 1033 - 1041» Kurzfassung anzeigen « Kurzfassung verbergen Kurzfassung We investigated the synthesis of one-dimensional nanostructures via Schiff base (imine) formation on three close-packed coinage metal (Au, Ag, and Cu) surfaces under ultrahigh vacuum conditions. We demonstrate the feasibility of forming pyrene-fused pyrazaacene-based oligomers on the Ag(111) surface by thermal annealing of tetraketone and tetraamine molecules, which were designed to afford cyclocondensation products. Direct visualization by scanning tunneling microscopy of reactants, intermediates, and products with submolecular resolution and the analysis’ of their statistical distribution in dependence of stoichiometry and annealing temperature together with the inspection of complementary X-ray photoelectron spectroscopy signatures provide unique insight in the reaction mechanism, its limitations, and the role of the supporting substrate. In contrast to the reaction on Ag(111), the reactants desorb from the Au(111) surface before reacting, whereas they decompose on the Cu(111) Surface during the relevant thermal treatment.Chakrabarti A , ... , Sippl W , Jung M Targeting histone deacetylase 8 as a therapeutic approach to cancer and neurodegenerative diseases 2016 FUTURE MEDICINAL CHEMISTRY , Band : 8, Nummer : 13, Seiten : 1609 - 1634Morera L , Luebbert M , Jung M Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy 2016 CLINICAL EPIGENETICS , Band : 8Lang D , van Gessel N , Ullrich KK , Reski R The Genome of the Model Moss Physcomitrella patens 2016 Adv Bot Res , Band : 78, Seiten : 97 - 140Pereman I , Mosquna A , Katz A , Wiedemann G , Lang D , Decker EL , Tamada Y , Ishikawa T , Nishiyama T , Hasebe M , Reski R , Ohad N The Polycomb group protein CLF emerges as a specific tri-methylase of H3K27 regulating gene expression and development in Physcomitrella patens. 2016 Biochim Biophys Acta , Band : 1859, Nummer : 7, Seiten : 860 - 870Burshtein G , Lumelsky V , Lifshitz Y The Role of Reactive Gases in ZnO Nanowires Growth via the Carbothermal Reaction 2016 Journal of Physical Chemistry C , Band : 120, Nummer : 28, Seiten : 15424 - 15435Haydl A , Breit B The Total Synthesis of Epothilone D as a Yardstick for Probing New Methodologies 2016 Chem. Eur. J. , Band : 23, Seiten : 541 - 545Weber A , Heinlein M , Dengjel J , Alber C , Singh PK , Hacker G The deubiquitinase Usp27x stabilizes the BH3-only protein Bim and enhances apoptosis. 2016 Embo Rep , Band : 17, Nummer : 5, Seiten : 724 - 738Zhang L , Trncik C , Andrade SLA , Einsle O The flavinyl transferase ApbE of Pseudomonas stutzeri matures the NosR protein required for nitrous oxide reduction 2016 Bba-bioenergetics , Band : 1858, Seiten : 95 - 102Wang Z , Kern JL , Laird BB The phase equilibrium, transport and local liquid structure of the methanol/water/ethylene ternary system: A molecular simulation study 2016 Fluid Phase Equilibr , Band : 429, Seiten : 275 - 280Bonardi A , Corlatti L , Bragalanti N , Pedrotti L The roles of weather and density dependence on population dynamics of Alpine-dwelling red deer. 2016 Integr Zool Tanveer Karim M , Stassun KG , Briceno C , Vivas AK , Raetz S , ... , Hackstein M The rotation period distributions of 4–10 Myr T Tauri stars in Orion OB1: New constraints on premain-sequence angular momentum evolution 2016 Astron J , Band : 152Campana F Thomas Abundance for Kähler threefolds 2016 Ann. Sci. Éc. Norm. Supér , Band : 49, Nummer : 4, Seiten : 971 - 1025Ostrovskyi D , Rumpf T , Eib J , Lumbroso A , Slynko I , Klaeger S , Heinzlmeir S , Forster M , Gehringer M , Pfaffenrot E , Bauer SM , Schmidtkunz K , Wenzler S , Metzger E , Kuster B , Schüle R , Sippl W , Breit B , Jung M Tofacitinib and analogs as inhibitors of the histone kinase PRK1 (PKN1 2016 Future Med Chem , Band : 8, Seiten : 1537 - 1551Samyn P Tribological properties and thermomechanical analysis of unsaturated polyester fabric composite in oscillating line-contact sliding 2016 TRIBOLOGY INTERNATIONAL , Band : 99, Seiten : 127 - 139Samyn P , Van Nieuwkerke D , Rastogi V , Stanssens D Tuning thermal release kinetics of soy oil from organic nanoparticles using variable synthesis conditions 2016 PARTICUOLOGY , Band : 26, Seiten : 54 - 65» Kurzfassung anzeigen « Kurzfassung verbergen Kurzfassung The thermal release properties of soy oil from poly(styrene-co-maleimide) nanoparticles containing 50 wt% encapsulated oil have been quantified as a function of temperature and time. The effects of different synthesis conditions on the thermal stability of the nanoparticles and their oil release have been evaluated, i.e., by gradually increasing the amount of ammonium hydroxide used for the imidization of poly(styrene-co-maleic anhydride). First, the intrinsic thermal properties of the oil-filled nanoparticles were analysed by differential scanning calorimetry, which revealed an exothermal reaction related to the oil release and a suppression of the glass transition that may be masked owing to the complex structure of the hybrid nanoparticles. The isothermal scans showed different rates of oil release after a post-imidization reaction. The oil release was better followed by dynamic mechanical analysis, which illustrated changes in visco-elastic properties expressed by the maximum in the loss factor that related to the amount of released oil. Depending on the amount of ammonium hydroxide, the oil started to release below the glass transition temperature at various rates. Thermal release profiles of the oil were quantified by infrared and Raman spectrocopy after heating for 2 min to 6 h at 125 to 250 degrees C, based on variations in oil-related and imide-related absorption bands. The oil release increased below and above the glass transition temperature, following a parabolic trend, and progressively decreased at higher ammonium hydroxide concentrations, in parallel with higher imide content and changes in imide conformation. The kinetics and mechanism of the oil release can be described by the Korsmeyer-Peppas model, suggesting a dominating diffusion mechanism that is influenced by further imidization of the polymer matrix during heating. (C) 2016 Chinese Society of Particuology and Institute of Process Engineering, Chinese Academy of Sciences. Published by Elsevier B.V. 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