Postdoc with Junior Fellow Jörn Dengjel
Macroautophagy is regarded as an unspecific bulk degradation process. However, using cell culture experiments we could show that organelles are degraded in an ordered fashion during starvation-induced macroautophagy. Currently, we are investigating starvation-induced, tissue-specific degradation dynamics in mice. The goal is to understand tissue-specific responses to starvation and the influence of macroautophagy on respective protein dynamics.