20. Hermann Staudinger Lecture mit Nobelpreisträger Andrew Z. Fire
Cellular Response to Genetic Change
Andrew Fire and Craig Mello were honoured with the Nobel Prize for Physiology or Medicine in 2006 for their discoveries related to gene silencing — a process that allows cells to selectively turn off specific genes.
| Wann |
07.10.2015 von 18:15 bis 20:00 |
|---|---|
| Wo | Hörsaal Pathologie/Anatomie, Albertstr. 19 |
| Name | Dr. Britta Küst |
| Kontakttelefon | +49 (0)761 203-97407 |
| Teilnehmer |
öffentlich / open to the public |
| Termin übernehmen |
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In his research, Andrew Fire primarily makes use of the nematode C. elegans in experimental studies. C. elegans is small, easily cultured, and can readily be made to accept foreign DNA or RNA. The results of such experiments have outlined a number of concerted responses that recognize (and in most cases work to silence) the foreign nucleic acid. One such mechanism ("RNAi") responds to double stranded character in RNA: either as introduced experimentally into the organism or as produced from foreign DNA that has not undergone selection to avoid a dsRNA response. Much of the current effort in the lab is directed toward a molecular understanding of the RNAi machinery and its roles in the cell. RNAi is not the only cellular defense against unwanted nucleic acid, and substantial current effort in the lab is also directed at identification of other triggers and mechanisms used in recognition and response to foreign information.
More information: http://firelab.stanford.edu/
Further information:
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