Publications 2013
2013
Scientific Journals:
- J. Speck, C. Rauber, T. Kukenshoner, C. Niemoller, K.J. Mueller, P. Schleberger, P. Dondapati, J. Hecky, K.M. Arndt, K.M. Muller: TAT hitchhiker selection expanded to folding helpers, multimeric interactions and combinations with protein fragment complementation. Protein Eng Des Sel, 2013; 26 (3): 225-242. http://dx.doi.org/10.1093/protein/gzs098
- A. Nystrom, L. Bruckner-Tuderman, J.S. Kern: Cell- and protein-based therapy approaches for epidermolysis bullosa. Methods Mol Biol, 2013; 961: 425-440. http://dx.doi.org/10.1007/978-1-62703-227-8_29
- A. Nystrom, D. Velati, V.R. Mittapalli, A. Fritsch, J.S. Kern, L. Bruckner-Tuderman: C7 plays a dual role in skin wound healing. J Invest Dermatol, 2013; 133 Suppl. 1: S256-S256.
- A. Nystrom, D. Velati, V.R. Mittapalli, J.S. Kern, A. Fritsch, L. Bruckner-Tuderman: Collagen VII plays a dual role in wound healing. J Clin Invest, 2013. (in press)
- A. Nystrom, J. Buttgereit, M. Bader, T. Shmidt, C. Ozcelik, I. Hausser, L. Bruckner-Tuderman, J.S. Kern: Rat Model for Dominant Dystrophic Epidermolysis Bullosa: Glycine Substitution Reduces Collagen VII Stability and Shows Gene-Dosage Effect. Plos One, 2013; 8 (5): e64243-e64243. http://dx.doi.org/10.1371/journal.pone.0064243
- A. Sprenger, V. Kuttner, L. Bruckner-Tuderman, J. Dengjel: Global Proteome Analyses of SILAC-Labeled Skin Cells. Methods Mol Biol, 2013; 961: 179-191. http://dx.doi.org/10.1007/978-1-62703-227-8_10
- C. Hunefeld, M. Mezger, J.S. Kern, A. Nystrom, L. Bruckner-Tuderman, R. Handgretinger, M. Rocken: One goal, different strategies - molecular and cellular approaches for the treatment of inherited skin fragility disorders. Exp Dermatol, 2013; 22(3): 162-167. http://dx.doi.org/10.1111/exd.12084
- D. Kiritsi, M. Pigors, I. Tantcheva-Poor, C. Wessel, M.J. Arin, J. Kohlhase, L. Bruckner-Tuderman, C. Has: Epidermolysis bullosa simplex ogna revisited. J Invest Dermatol, 2013; 133 (1): 270-273. http://dx.doi.org/10.1038/jid.2012.248
- S.C. Hofmann, A. Bosma, L. Bruckner-Tuderman, M. Vukmanovic-Stejic, E.C. Jury, D.A. Isenberg, C. Mauri: Invariant natural killer T cells are enriched at the site of cutaneous inflammation in lupus erythematosus. J Dermatol Sci, 2013; 71 (1): 22-28. http://dx.doi.org/10.1016/j.jdermsci.2013.04.012
- V. Küttner, C. Mack, K. TG Rigbolt, J. S Kern, O. Schilling, H. Busch, L. Bruckner-Tuderman, J. Dengjel: Global remodelling of cellular microenvironment due to loss of collagen VII. Molecular Systems Biology, 2013. http://www.nature.com/msb/journal/v9/n1/full/msb201317.html
- V.I. Dumit, V. Kuttner, J. Kappler, S. Piera-Velazquez, S.A. Jimenez, L. Bruckner-Tuderman,J. Uitto, J. Dengjel: Resemblances between scleroderma and ageing in skin fibroblasts. J Invest Dermatol, 2013; 133 Suppl. 1: S156-S156.
- A. Sprenger, S. Weber, M. Zarei, R. Engelke, J.M. Nascimento, C. Gretzmeier, M. Hilpert, M. Boerries, C. Has,H. Busch, L. Bruckner-Tuderman, J. Dengjel: Consistency of the proteome in primary human keratinocytes with respect to gender, age, and skin localization. Mol Cell Proteomics, 2013. http://dx.doi.org/10.1074/mcp.M112.025478
- H. Busch, M. Boerries, J. Bao, S.T. Hanke, M. Hiss, T. Tiko, S.A. Rensing: Network theory inspired analysis of time-resolved expression data reveals key players guiding P. patens stem cell development. Plos One, 2013; 8 (4): e60494-e60494. http://dx.doi.org/10.1371/journal.pone.0060494
- M. Boerries, F. Grahammer, S. Eiselein, M. Buck, C. Meyer, M. Goedel, W. Bechtel, S. Zschiedrich, D. Pfeifer, D. Laloe, C. Arrondel, S. Goncalves, M. Kruger, S.J. Harvey, H. Busch, J. Dengjel, T.B. Huber: Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks. Kidney Int, 2013. http://dx.doi.org/10.1038/ki.2012.487
- M. Buck, D. Saltukoglu, M. Boerries, M. Simons, H. Busch: A distributed stochastic perception-action loop model of cell motility. IEEE Conference Proceedings, 2013. [in Druck]
- S. Tholen, M.L. Biniossek, M. Gansz, A. Gomez-Auli, F. Bengsch, A. Noel, J.N. Kizhakkedathu, M. Boerries, H. Busch, T. Reinheckel, O. Schilling: Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome. Mol Cell Proteomics, 2013; 12 (3): 611-625. http://dx.doi.org/10.1074/mcp.M112.017962
- F. Nazio, F. Strappazzon, M. Antonioli, P. Bielli, V. Cianfanelli, M. Bordi, C. Gretzmeier, J. Dengjel, M. Piacentini, G.M. Fimia, F. Cecconi: mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6. Nat Cell Biol, 2013; 15 (4): 406-416. http://dx.doi.org/10.1038/ncb2708
- M. Fischer, S. Horn, A. Belkacemi, K. Kojer, C. Petrungaro, M. Habich, m. Ali, V. Kuttner, M. Bien, F. Kauff, J. Dengjel, J.M. Herrmann, J. Riemer: Protein import and oxidative folding in the mitochondrial intermembrane space of intact mammalian cells. Mol Biol Cell, 2013. http://dx.doi.org/10.1091/mbc.E12-12-0862
- S. Halbach, K.T. Rigbolt, F.U. Wohrle, B. Diedrich, C. Gretzmeier, T. Brummer, J. Dengjel: Alterations of Gab2 signalling complexes in imatinib and dasatinib treated chronic myeloid leukaemia cells. Cell Commun Signal, 2013; 11 (1): 30-30. http://dx.doi.org/10.1186/1478-811X-11-30
- J. Schweitzer, H. Lohr, J.L. Bonkowsky, K. Hubscher, W. Driever: Sim1a and Arnt2 contribute to hypothalamo-spinal axon guidance by regulating Robo2 activity via a Robo3-dependent mechanism. Development, 2013; 140 (1): 93-106. http://dx.doi.org/10.1242/dev.087825
- S. Song, S. Eckerle, D. Onichtchouk, J.A. Marrs, R. Nitschke, W. Driever: Pou5f1-Dependent EGF Expression Controls E-Cadherin Endocytosis, Cell Adhesion, and Zebrafish Epiboly Movements. Developmental Cell, 2013; 24 (5): 486-501. http://dx.doi.org/10.1016/j.devcel.2013.01.016
- H.P. Ren, M.S. Baptista, C. Grebogi: Wireless communication with chaos. Phys Rev Lett, 2013; 110 (18): 184101.
- H. Xu, L. Huang, Y.C. Lai, C. Grebogi: Chiral scars in chaotic dirac fermion systems. Phys Rev Lett, 2013; 110 (6): 064102.
- R. Yang, L. Huang, Y.C. Lai, C. Grebogi, L.M. Pecora: Harnessing quantum transport by transient chaos. Chaos, 2013; 23 (1): 013125. http://dx.doi.org/10.1063/1.4790863
- A. Sharaf, K. Krieglstein, B. Spittau: Distribution of microglia in the postnatal murine nigrostriatal system. Cell Tissue Res, 2013; 351 (3): 373-382. : http://dx.doi.org/10.1007/s00441-012-1537-y
- B. Spittau, L. Wullkopf, X. Zhou, J. Rilka, D. Pfeifer, K. Krieglstein: Endogenous transforming growth factor-beta promotes quiescence of primary microglia in vitro. Glia, 2013; 61 (2): 287-300. : http://dx.doi.org/10.1002/glia.22435
- S. Heermann, K. Matlik, U. Hinz, J. Fey, U. Arumae, K. Krieglstein: Glia cell line-derived neurotrophic factor mediates survival of murine sympathetic precursors. J Neurosci Res, 2013. : http://dx.doi.org/10.1002/jnr.23188
- S. Knauer, A.L. Holt, I. Rubio-Somoza, E.J. Tucker, A. Hinze, M. Pisch, M. Javelle, M.C. Timmermans, M.R. Tucker, T. Laux: A protodermal miR394 signal defines a region of stem cell competence in the Arabidopsis shoot meristem. Dev Cell, 2013; 24 (2): 125-132. http://dx.doi.org/10.1016/j.devcel.2012.12.009
- S. Demeyer, T. Michoel, J. Fostier, P. Audenaert, M. Pickavet, P. Demeester: The Index-Based Subgraph Matching Algorithm (ISMA): Fast Subgraph Enumeration in Large Networks Using Optimized Search Trees. Plos One, 2013; 8 (4): e61183-e61183.
- C. Stadler, E. Rexhepaj, V.R. Singan, R.F. Murphy, R. Pepperkok, M. Uhlen, J.C. Simpson, E. Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. Nat Methods, 2013. http://dx.doi.org/10.1038/nmeth.2377
- S. Weber, M.L. Fernandez-Cachon, J.M. Nascimento, S. Knauer, B. Offermann, R.F. Murphy, M. Boerries, H. Busch: Label-Free Detection of Neuronal Differentiation in Cell Populations Using High-Throughput Live-Cell Imaging of PC12 Cells Plos One, 2013; 8: e56690.
- M.K. Singh, F. Ren, T. Giesemann, C.D. Bosco, T.P. Pasternak, T. Blein, B. Ruperti, G. Schmidt, K. Aktories, A.J. Molendijk, K. Palme: Modification of plant Rac/Rop GTPase signalling using bacterial toxin transgenes. Plant J, 2013; 73 (2): 314-324. http://dx.doi.org/10.1111/tpj.12040
- S. Rigas, F.A. Ditengou, K. Ljung, G. Daras, O. Tietz, K. Palme, P. Hatzopoulos: Root gravitropism and root hair development constitute coupled developmental responses regulated by auxin homeostasis in the Arabidopsis root apex. New Phytol, 2013; 197 (4): 1130-1141. http://dx.doi.org/10.1111/nph.12092
- J. Harb, O. Saleh, D. Kittemann, D.A. Neuwald, W. Frank, R. Reski: Upregulation of polyphenol-related genes prevents ‘skin burning’ of well-colored ‘Cameo’ apples stored under stressful controlled atmosphere conditions. Postharvest Biol Tec, 2013; 77: 121-127.
- L. Cooper, R.L. Walls, J. Elser, M.A. Gandolfo, D.W. Stevenson, B. Smith, J. Preece, B. Athreya, C.J. Mungall, S. Rensing, M. Hiss, D. Lang, R. Reski, T.Z. Berardini, D. Li, E. Huala, M. Schaeffer, N. Menda, E. Arnaud, R. Shrestha, Y. Yamazaki, P. Jaiswal: The Plant Ontology as a tool for comparative plant anatomy and genomic analyses. Plant and Cell Physiology, 2013; 54 (2): 1-23. doi: 10.1093/pcp/pcs163
- N. Wangler, M. Welsche, M. Blazek, M. Blessing, M. Vervliet-Scheebaum, R. Reski, C. Muller, H. Reinecke, J. Steigert, G. Roth, R. Zengerle, N. Paust: Bubble Jet agent release cartridge for chemical single cell stimulation. Biomed Microdevices, 2013; 15 (1): 1-8. http://dx.doi.org/10.1007/s10544-012-9681-4
- S.Y. Kim, C.C. Colpitts, G. Wiedemann, C. Jepson, M. Rahimi, J.R. Rothwell, A.D. McInnes, M. Hasebe, R. Reski, B.T. Sterenberg, D.Y. Suh: Physcomitrella PpORS, basal to plant type III polyketide synthases in phylogenetic trees, is a very long chain 2'-oxoalkylresorcinol synthase. J Biol Chem, 2013; 288 (4): 2767-2777. http://dx.doi.org/10.1074/jbc.M112.430686
- A. Yalcin, C. Kreutz, D. Pfeifer, M. Abdelkarim, G. Klaus, J. Timmer, M. Lubbert, B. Hackanson: MeDIP coupled with a promoter tiling array as a platform to investigate global DNA methylation patterns in AML cells. Leukemia Res, 2013; 37 (1): 102-111. http://dx.doi.org/10.1016/j.leukres.2012.09.014
- A. Raue, C. Kreutz, F.J. Theis, J. Timmer: Joining forces of Bayesian and frequentist methodology: a study for inference in the presence of non-identifiability. Philos T Roy Soc A, 2013; 371 (1984): 20110544-20110544. http://dx.doi.org/10.1098/rsta.2011.0544
- C. Kreutz, A. Raue, D. Kaschek, J. Timmer: Profile likelihood in systems biology. Febs J, 2013; 280 (11): 2564-2571. http://dx.doi.org/10.1111/febs.12276
- K. Aumann, A.V. Frey, A.M. May, D. Hauschke, C. Kreutz, J.P. Marx, J. Timmer, M. Werner, H.L. Pahl: Subcellular mislocalization of the transcription factor NF-E2 in erythroid cells discriminates pre-fibrotic primary myelofibrosis from essential thrombocythemia. Blood, 2013. http://dx.doi.org/10.1182/blood-2012-11-463257
- K. Muller, R. Engesser, S. Metzger, S. Schulz, M.M. Kampf, M. Busacker, T. Steinberg, P. Tomakidi, M. Ehrbar, F. Nagy, J. Timmer, M.D. Zubriggen, W. Weber: A red/far-red light-responsive bi-stable toggle switch to control gene expression in mammalian cells. Nucleic Acids Res, 2013. http://dx.doi.org/10.1093/nar/gkt002
- K. Muller, R. Engesser, S. Schulz, T. Steinberg, P. Tomakidi, C.C. Weber, R. Ulm, J. Timmer M.D. Zurbriggen, W. Weber: Multi-chromatic control of mammalian gene expression and signaling. Nucleic Acids Res, 2013. http://dx.doi.org/10.1093/nar/gkt340
- M. Mischnik, D. Boyanova, K. Hubertus, J. Geiger, N. Philippi, M. Dittrich, G. Wangorsch, J. Timmer, T. Dandekar: A Boolean view separates platelet activatory and inhibitory signalling as verified by phosphorylation monitoring including threshold behaviour and integrin modulation. Mol Biosyst, 2013. : http://dx.doi.org/10.1039/c3mb25597b
- V. Morath, M. Keuper, M. Rodriguez-Franco, S. Deswal, G. Fiala, B. Blumenthal, D. Kaschek, J. Timmer, G. Neuhaus, S. Ehl, O. Ronneberger, W.W. Schamel: Semi-automatic determination of cell surface areas used in systems biology . Front Biosci (Elite Ed), 2013; 5: 533-545.
- G. Akoglu, Q. Li, O. Gokoz, A.S. Gazyagci, J. Uitto: Clinical and histopathological characteristics of a family with R1141X mutation of pseudoxanthoma elasticum - presymptomatic testing and lack of carrier phenotypes. Int J Dermatol, 2013. href="http://dx.doi.org/10.1111/ijd.12008
- J. Uitto, A. Varadi, L. Bercovitch, P.F. Terry, S.F. Terry: Pseudoxanthoma Elasticum: Progress in Research Toward Treatment: Summary of the 2012 PXE International Research Meeting. J Invest Dermatol, 2013; 133 (6): 1444-1449. http://dx.doi.org/10.1038/jid.2013.20
- M. El-Domyati, T.S. El-Ammawi, W. Medhat, O. Moawad, M.G. Mahoney, J. Uitto: Expression of p53 Protein After Nonablative Rejuvenation: The Other Side of the Coin. Dermatol Surg, 2013. : http://dx.doi.org/10.1111/dsu.12145
- C.S. Faria, Q. Li, H. Guo, J. Uitto, S.S. Takeno, S.M. de Arruda Cardoso, D.V. Freire-Maia: Clinical Phenotypes and ABCC6 Gene Mutations in Brazilian Families with Pseudoxanthoma Elasticum. Acta Derm-venereol, 2013. : http://dx.doi.org/10.2340/00015555-1570
- Q. Li, H. Guo, D. Chou, D.J. Harrington, L.J. Schurgers, S.F. Terry, J. Uitto: Warfarin Accelerates Ectopic Mineralization in Abcc6(-/-) Mice: Clinical Relevance to Pseudoxanthoma Elasticum. Am J Pathol, 2013. : http://dx.doi.org/10.1016/j.ajpath.2012.12.037
- Q. Li, J. Uitto: Mineralization/Anti-Mineralization Networks in the Skin and Vascular Connective Tissues. Am J Pathol, 2013. http://dx.doi.org/10.1016/j.ajpath.2013.03.002
- Q. Li, J. Uitto: Zebrafish as a model system to study heritable skin diseases. Methods Mol Biol, 2013; 961: 411-424. http://dx.doi.org/10.1007/978-1-62703-227-8_28
- V. Alexeev, A. Donahue, J. Uitto, O. Igoucheva: Analysis of chemotactic molecules in bone marrow-derived mesenchymal stem cells and the skin: Ccl27-Ccr10 axis as a basis for targeting to cutaneous tissues. Cytotherapy, 2013; 15 (2): 171-184.e1. http://dx.doi.org/10.1016/j.jcyt.2012.11.006
- X. Wang, P. Ghasri, M. Amir, B. Hwang, Y. Hou, M. Khilili, A. Lin, D. Keene, J. Uitto, D.T. Woodley, M. Chen: Topical Application of Recombinant Type VII Collagen Incorporates Into the Dermal-Epidermal Junction and Promotes Wound Closure. Mol Ther, 2013. http://dx.doi.org/10.1038/mt.2013.8
- Y. Zhou, Q. Jiang, S. Takahagi, C. Shao, J. Uitto: Premature Termination Codon Read-Through in the ABCC6 Gene: Potential Treatment for Pseudoxanthoma Elasticum. J Invest Dermatol, 2013. http://dx.doi.org/10.1038/jid.2013.234
Scientific Staff:
- A.C. Alvarez, G. Hime, J.D. Silva, D. Marchesin: Analytic regularization of an inverse filtration problem in porous media. Inverse Problems, 2013; 29 (2): 025006.