Juliana M. Nascimento
Postdoc with Junior Fellow Hauke Busch
Juliana M. Nascimento received her B. Sc. degree in Biology in 2002 at the University of Campinas, Brazil, working with Biochemistry of P450 protein systems at the Institute of Biology. The Ph.D occurred from 2003-2008 in the Biochemistry in the Institute of Biology from University of Campinas, Brazil, under supervision of Dr. Stephen Hyslop and Dr. Carla Collares-Buzato. The main subject of the PhD thesis was to study the mechanisms of cell death in mammalian cells caused by snake venom toxins, using chromatographic techniques, enzimology, biochemistry and molecular cell biology approaches. After PhD, from March 2008-2009 she worked as a postdoctoral fellow at the Pharmacology of the Faculty of Medical Sciences, University of Campinas, Brazil. Since April 2009 she joined the Freiburg Institute for Advanced Studies (FRIAS) at the Albert-Ludwigs University Freiburg as a postdoctoral fellow in the research group of Hauke Busch.
- J.M. Nascimento, G.C. Franchi, A.E. Nowill, C.B. Collares-Buzato, S. Hyslop (2007) Cytoskeletal rearrangement and cell death induced by Bothrops alternatus snake venom in cultured Madin-Darby canine kidney cells, Biochemistry and Cell Biology, 85, 591-605
- D.C.S. Damico, J.M. Nascimento, L. Ponce-Soto, B. Lomonte, P.P. Joazeiro, S. Marangoni, J.C. Novello, C.B. Collares-Buzato (2007) Cytotoxicity of Lachesis muta muta snake venom and its purified basic phospholipase A2 (LMTX-I) in cultured cells, Toxicon, 49 (5), 678-692
Systems Biology of cellular decisions and cell-cell communication of skin
The group of Hauke Busch focuses on the development and verification of mathematical models for cellular behavior from an initial stimulus to the final phenotype. In a systems biology approach we combine experimental research on cell-cell communication with the development of appropriate multi-scale dynamic models to investigate the necessary and sufficient control points that lead to cell proliferation, differentiation, migration or death.