Dinner Speech - Conrad Mullineaux: What’s it like inside a bacterium?
Nov 05, 2014
from 06:30 PM to 07:00 PM
|Where||FRIAS, Albertstr. 19, Seminar Room|
|Contact Name||Nikolaus Binder|
|Contact Phone||+49 (0)761 203-97398|
universitätsoffen / open to university members
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Conrad Mullineaux: What’s it like inside a bacterium?
My group works on several different kinds of bacteria and some very diverse specific problems in bacterial cell biology, but the underlying theme is to try understand how bacterial cells work as physical and chemical systems. “Omics” data has given us a complete list of the components of many bacteria, but we don’t know what a lot of them are for. Even when we have some idea what a particular protein does for the cell, we often don’t understand how it does it. We find that it helps a lot if we know where the protein is located in the cell, how it can move and what it interacts with. A good first step is to put a fluorescent tag on the protein and then use fluorescence microscopy to observe it in action in live cells. I will discuss the advantages and limitations of this approach, and illustrate it with some specific examples in cyanobacteria and Escherichia coli.