Artikelaktionen

Sie sind hier: FRIAS Wissenschaftliche … Archiv Wissenschaftliche … Martin Klose

Martin Klose

Jedes Jahr werden etwa 50 Fellows eingeladen, die am FRIAS für zwei bis 12 Monate in einer intellektuell stimulierenden Atmosphäre an ihrem Projekt arbeiten können. Über das spezielle Alumni-Programm können Fellows, die ihre Tätigkeit am FRIAS bereits beendet haben, für zwei bis sechs Wochen erneut einen Forschungsaufenthalt am FRIAS beantragen, um z.B. begonnene Projekte abzuschließen. Daneben werden regelmäßig Junior- und Senior-WissenschaftlerInnen – meist zu Kooperationen mit den Fellows - für kürzere Zeit als GastwissenschaftlerInnen an das Institut eingeladen.

Schätz

Our Research Focus profited enormously from the international team of Fellows and guest researchers at FRIAS.

Prof. Dr. Tobias Schätz, ERC Consolidator Grant 2015, Research Focus Quantum Transport 2014/15

Biochemistry
Molecular Medicine and Cell Research
Postdoc with PI Melanie Börries

Systems Biology of Cellular Microenvironment 
AG Busch/Börries
German Cancer Consortium (DKTK)
Institute of Molecular Medicine and Cell Research
Albert-Ludwigs-University Freiburg
Stefan-Meyer Straße 17

79104 Freiburg

Tel. +49 (0)761-203 9619

CV

Martin finished his diploma in Biochemistry in 2005 at the University of Bayreuth. In 2005 he started his PhD thesis under supervision of Prof. Dr. Markus Missler at the Center of Physiology and Pathophysiology at the University Göttingen. In 2006 he moved with the group to the Department of Anatomy at the University Münster, where he completed in 2010 his PhD thesis. The main subject of his thesis was to study the molecular interactions of the transsynaptic Neurexin-Neuroligin-Neurexophilin-Complex. In August 2011, he joined Melanie Börries within the group of Hauke Busch as a postdoctoral fellow in the School for Life Science-LifeNet at FRIAS located at the ZBSA.

 

Within the BMBF funded Nephage consortium, Martin Klose uses a systems biology approach to understand molecular processes of ageing in the kidney through the in vitro study of podocytes, the most vulnerable cell type. Based on high-throughput analysis of primary podocytes, comparison with other organisms like Drosophila flies and C. elegans worms and signaling pathway analysis, he investigates the dynamic response and compensation processes in young and old immortalized podocyte strains. This will provide a complementary and well standardized system to reveal the processes of kidney ageing.

 

Selected Publications

  • C. Reissner, M. Klose, R. Fairless, M. Missler (2008). Mutational analysis of the neurexin/neuroligin complex reveals essential and regulatory components. Proc Natl Acad Sci USA 105, 15124-15129.