Dr. Andreas Manz: ""Lab on a Chip" - or how to play the scaling laws"
von 11:15 bis 12:15
|Wo||IMTEK , Fakultätsratzimmer, Institut für Mikrosystemtechnik, Georges-Köhler-Allee 101, 79110 Freiburg|
|Name||Prof. Gerald Urban|
Dr. Andreas Manz
Sensory Design and Technology Ltd.
St John's Innovation Centre, Cowley Road, Cambridge CB4 OWS
"Lab on a Chip" - or how to play the scaling laws
Microfluidic chips have been developed and applied to various fields. Particularly, fast separations and chemical reactions for use in analytical chemistry context have been of interest . Scaling laws predict a higher mass and heat transport for smaller dimensions. However, there is a trade-off between internal volumes and detection limits. For biology, the situation is not changing that much. However, due to the similarity of length scale of biological cells and channels on chip, new tools for the biologists may arise. Key applications include drug discovery , systems biology and regenerative medicine research.
In this presentation, I will briefly review scaling laws, show examples of microfluidic chips for electrophoresis, elaborate on work-in-progress with cell differentiation and give an example how mishaps turn out to be quite interesting….
 D.Janasek, J.Franzke, A.Manz, Nature 442, 374-380 (2006); J.West, M.Becker, S.Tombrink, A.Manz, Anal. Chem 80, 4403-4419 (2008)
 P.S.Dittrich, A.Manz, Nature Reviews Drug Discovery, 5, 210-218 (2006)