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Nikolaus Rajewsky: "Circular RNAs"

Wann 06.05.2013
von 11:15 bis 12:00
Wo ZBSA, Seminar Room -01.026, Freiburg, Germany
Kontakttelefon +49 761 203 97418
Teilnehmer Open to University members
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Nikolaus Rajewsky

The Berlin Institute for Medical Systems Biology, Germany

Circular RNAs

We have identified thousands of stably expressed circular RNAs (circRNAs), often showing tissue- or developmental-stage-specific expression. I will present biochemical, computational, and functional data which provide evidence that circRNAs form a class of previously overlooked post-transcriptional regulators. I will also discuss mechanisms for circRNA biogenesis and possible functions independent of miRNAs.