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Publikationen 2012


Originalarbeiten in wissenschaftlichen Fachzeitschriften:

  1. J. Speck, J. Hecky, H.-K. Tam, K. M. Arndt, O. Einsle, K. M. Mueller: Exploring the Molecular Linkage of Protein Stability Traits for Enzyme Optimization by Iterative Truncation and Evolution. Biochemistry, 2012; 51 (24): 4850-4867.
  2. C. Fatouros, G.J. Pir, J. Biernat, S.P. Koushika, E. Mandelkow, E.M. Mandelkow, E. Schmidt, R. Baumeister: Inhibition of Tau aggregation in a novel C. elegans model of Tauopathy mitigates proteotoxicity. Hum Mol Genet, 2012.
  3. P. Dalle Pezze, A.G. Sonntag, A. Thien, M.T. Prentzell, M. Godel, S. Fischer, E. Neumann-Haefelin, T.B. Huber, R. Baumeister, D.P. Shanley, K. Thedieck: A Dynamic Network Model of mTOR Signaling Reveals TSC-Independent mTORC2 Regulation. Sci Signal, 2012; 5 (217): ra25.
  4. S. Liu, E. Schulze, R. Baumeister: Temperature- and Touch-Sensitive Neurons Couple CNG and TRPV Channel Activities to Control Heat Avoidance in Caenorhabditis elegans. Plos One, 2012; 7 (3): e32360.
  5. W. Qi, X. Huang, E. Neumann-Haefelin, E. Schulze,  R. Baumeister: Cell-Nonautonomous Signaling of FOXO/DAF-16 to the Stem Cells of Caenorhabditis elegans. PLOS Genetics, 2012; 8: e1002836.
  6. A. Sesarman, E. Oswald, M.T. Chiriac, K. Csorba, V. Vuta, V. Feldrihan, A. Baican, L. Bruckner-Tuderman, C. Sitaru: Why human pemphigoid autoantibodies do not trigger disease by the passive transfer into mice? Immunol Lett, 2012;
  7. A.W. Arnold, D. Kiritsi, R. Happle, J. Kohlhase, I. Hausser, L. Bruckner-Tuderman, C. Has, P.H. Itin: Type 1 Segmental Galli-Galli Disease Resulting from a Previously Unreported Keratin 5 Mutation. J Invest Dermatol, 2012;
  8. C. Has, G. Sparta, D. Kiritsi, L. Weibel, A. Moeller, V. Vega-Warner, A. Waters, Y. He, Y. Anikster, P. Esser, B.K. Straub, I. Hausser, D. Bockenhauer, B. Dekel, F. Hildebrandt, L. Bruckner-Tuderman, G.F. Laube: Integrin alpha3 mutations with kidney, lung, and skin disease. New Engl J Med, 2012; 366 (16): 1508-1514.
  9. C.W. Franzke, C. Cobzaru, A. Triantafyllopoulou, S. Loffek, K. Horiuchi, D.W. Threadgill, T. Kurz, N. van Rooijen, L. Bruckner-Tuderman, C.P.Blobel: Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation. J Exp Med, 2012.
  10. D. Kiritsi, M. Pigors, I. Tantcheva-Poor, C. Wessel, M.J. Arin, J. Kohlhase, L. Bruckner-Tuderman, C. Has: Epidermolysis Bullosa Simplex Ogna Revisited. J Invest Dermatol, 2012; doi:10.1038/jid.2012.248
  11. D. Kiritsi, Y. He, A. M.G. Pasmooij, M. Onder, R. Happle, M. Jonkman, L. Bruckner-Tuderman, C. Has: Revertant mosaicism in a human skin fragility disorder results from slipped mispairing and mitotic recombination. J Clin Invest. 2012; 122(5): 1742–1746. doi:10.1172/JCI61976
  12. D.T. Behrens, D. Villone, M. Koch, G. Brunner, L. Sorokin, H. Robenek,L. Bruckner-Tuderman, P. Bruckner, U. Hansen: The epidermal basement membrane is a composite of separate laminin- or collagen IV-containing networks connected by aggregated perlecan, but not by nidogens. J Biol Chem, 2012;
  13. E. Oswald, A. Sesarman, C.W. Franzke, U. Wolfle, L. Bruckner-Tuderman, T. Jakob, S.F. Martin, C. Sitaru: The flavonoid luteolin inhibits fcgamma-dependent respiratory burst in granulocytes, but not skin blistering in a new model of pemphigoid in adult mice. Plos One, 2012; 7 (2): e31066.
  14. M. Pigors, D. Kiritsi, C. Cobzaru, A. Schwieger-Briel, J. Suarez, F. Faletra, H. Aho, L. Makela, J.S. Kern, L. Bruckner-Tuderman, C. Has: TGM5 Mutations Impact Epidermal Differentiation in Acral Peeling Skin Syndrome. J Invest Dermatol, 2012.
  15. S. Loffek, L. Bruckner-Tuderman, T.M. Magin: Involvement of the ubiquitin-proteasome system in the stabilization of cell-cell contacts in human keratinocytes. Exp Dermato, 2012.
  16. T. Hurskainen, J. Moilanen, R. Sormunen, C.W. Franzke, R. Soininen, S. Loeffek, L. Huilaja, M. Nuutinen, L. Bruckner-Tuderman, H. Autio-Harmainen, K. Tasanen: Transmembrane collagen XVII is a novel component of the glomerular filtration barrier. Cell Tissue Res, 2012;
  17. W. Nishie, J. Jackow, S.C. Hofmann, C.W. Franzke, L. Bruckner-Tuderman: Coiled-coils ensure the physiological ectodomain shedding of collagen XVII. J Biol Chem, 2012.
  18. A. Singh, J.M. Nascimento, S. Kowar, H. Busch, M. Börries: Boolean approach to signalling pathway modelling in HGF-induced keratinocyte migration. Bioinformatics, 2012; 28 (18); i495-i501.
  19. V. Kuettner,  C. Mack,  K. Rigbolt,  O. Schilling,  H. BuschL. Bruckner-TudermanJ. Dengjel: Disease proteomics reveals modulation of cell microenvironment in recessive dystrophic epidermolysis bullosa. Journal of Investigative Dermatology, 2012; 132: S45.
  20. A. Matheu, M. Collado, C. Wise, L. Manterola, L. Cekaite, A.J. Tye, M. Canamero, L. Bujanda, A. Schedl, K.S. Cheah, R.I. Skotheim, R.A. Lothe, A. Lopez de Munain, J. Briscoe, M. Serrano, R. Lovell-Badge: Oncogenicity of the developmental transcription factor Sox9. Cancer Res, 2012; 72 (5): 1301-1315.
  21. I. Grskovic, A. Kutsch, C. Frie, G. Groma, J. Stermann, U. Schlotzer-Schrehardt, A. Niehoff, S.E. Moss, S. Rosenbaum, E. Poschl, M. Chmielewski, G. Rappl, H. Abken, J.F. Bateman, K.S. Cheah, M. Paulsson, B. Brachvogel: Depletion of annexin A5, annexin A6 and collagen X causes no gross changes in matrix vesicle mediated mineralization, but lack of collagen X affects hematopoiesis and the Th1/Th2 response. J Bone Miner Res, 2012.
  22. Q. Yuan, H. Su, J. Guo, K.Y. Tsang, K.S. Cheah, K. Chiu, J. Yang, W.M. Wong, K.F. So, J.D. Huang, W. Wu, Z.X. Lin: Decreased c-Jun expression correlates with impaired spinal motoneuron regeneration in aged mice following sciatic nerve crush. Exp Gerontol, 2012; 47 (4): 329-336.
  23. Y.H. Fan, y.Q. Song, D. Chan, Y. Takahashi, S. Ikegawa, M. Matsumoto, I. Kou, K.S. Cheah, P. Sham, K.M. Cheung, K.D. Luk: SNP rs11190870 near LBX1 is associated with adolescent idiopathic scoliosis in southern Chinese. J Hum Genet, 2012; 57 (4): 244-246.
  24. A.C. Becker, J. Bunkenborg, T. Eisenberg, L.M. Harder, S. Schroeder, F. Madeo, J.S. Andersen, J. Dengjel: Friend or food: Different cues to the autophagosomal proteome. Autophagy, 2012; 8 (6).
  25. A. Schreiber, Y. Yuan, M.C. Huber, R. Thomann, A. Ziegler, H. Coelfen, J. Dengjel, M. Krueger, S.M. Schiller: From Bioconjugation to Self-Assembly in Nanobiotechnology: Quantum Dots Trapped and Stabilized by Toroid Protein Yoctowells. Advanced Engineering Materials, 2012; 14 (6): B344-B350.
  26. G. Fuellen, J. Dengjel, A. Hoeflich, J. Hoeijmakers, H.A. Kestler, A. Kowald, S. Priebe, D. Rebholz-Schuhmann, B. Schmeck, U. Schmitz, A. Stolzing, J. Suhnel, D. Wuttke, J. Vera: Systems Biology and Bioinformatics in Aging Research: A Workshop Report. Rejuv Res, 2012.
  27. J. Dengjel, M. Zarei, A. Sprenger, C. Gretzmeier: Combinatorial use of ERLIC and SCX chromatography for in-depth phosphoproteome analysis. J Proteome Res, 2012; 8(6).
  28. J. Dengjel, M. Hoyer-Hansen, M.O. Nielsen, T. Eisenberg, L.M. Harder, S. Schandorff, T. Farkas, T. Kirkegaard, A.C. Becker, S. Schroeder, K. Vanselow, E. Lundberg, M.M. Nielsen, A.R. Kristensen, V. Akimov, J. Bunkenborg, F. Madeo, M. Jaattela, J.S. Andersen: Identification of autophagosome-associated proteins and regulators by quantitative proteomic analysis and genetic screens. Mol Cell Proteomics, 2012; 11(3).
  29. L Bozzacco, H. Yu, J. Dengjel C. Trumpfheller, H.A. Zebroski, N. Zhang, V. Kuettner, B.M. Ueberheide, H. Deng, B.T. Chait, R.M. Steinman, S. Mojsov, D. Fenyoe:
    Strategy for Identifying Dendritic Cell-Processed CD4(+) T Cell Epitopes from the HIV Gag p24 Protein. PLOS ONE, 2012; 7: e41897.
  30. R. Engelke, A.C. Becker, J. Dengjel: The Degradative Inventory of the Cell: Proteomic Insights. Antioxid Redox Sign, 2012;
  31. V.I. Dumit, J. Dengjel: Autophagosomal protein dynamics and influenza virus infection. Front Immunol, 2012; 3: 43.
  32. A. Filippi, C. Jainok, W. Driever: Analysis of transcriptional codes for zebrafish dopaminergic neurons reveals essential functions of Arx and Isl1 in prethalamic dopaminergic neuron development.Dev Biol, 2012.
  33. A.M. Fernandes, K. Fero, A.B. Arrenberg, S.A. Bergeron, W. Driever, H.A. Burgess: Deep Brain Photoreceptors Control Light-Seeking Behavior in Zebrafish Larvae.Curr Biol, 2012.
  34. J. Schweitzer, H. Loehr, A. Filippi, W. Driever: Dopaminergic and noradrenergic circuit development in zebrafish. Developmental Neurobiology, 2012; 72 (3): 256-268.
  35. M. Manoli, W. Driever: Fluorescence-Activated Cell Sorting (FACS) of Fluorescently Tagged Cells from Zebrafish Larvae for RNA Isolation. Cold Spring Harb Protoc, 2012; 2012 (8).
  36. O. Ronneberger, K. Liu, M. Rath, D. Ruebeta, T. Mueller, H. Skibbe, B. Drayer, T. Schmidt, A. Filippi, R. Nitschke, T. Brox, H. Burkhardt, W. Driever: ViBE-Z: a framework for 3D virtual colocalization analysis in zebrafish larval brains.Nat Methods, 2012.
  37. J.E. Christensen, C. Fenger, S. Issazadeh-Navikas, A. Krug, P. Liljestrom, S. Goriely, S.R. Paludan, B. Finsen, J.P. Christensen, A.R. Thomsen: Differential impact of interferon regulatory factor 7 in the initiation of the type I interferon response in the LCMV infected CNS versus the periphery. J Virol, 2012;
  38. K.L. Lambertsen, K. Biber, B. Finsen: Inflammatory cytokines in experimental and human stroke. J Cerebr Blood F Met, 2012; 32 (9): 1677-1698.
  39. M. Bloksgaard, S. Bek, A.B. Marcher, D. Neess, J. Brewer, H.K. Hannibal-Bach, T. Helledie, C. Fenger, M. Due, Z. Berzina, R. Neubert, J. Chemnitz, B. Finsen, A. Clemmensen, J. Wilbertz, H. Saxtorph, J. Knudsen, L. Bagatolli, S. Mandrup: The Acyl CoA Binding Protein is required for Normal Epidermal Barrier Function in Mice. J Lipid Res, 2012;
  40. A.B. Schelin, G. Karolyi, A.P. de Moura, N. Booth, C. Grebogi: Are the fractal skeletons the explanation for the narrowing of arteries due to cell trapping in a disturbed blood flow? Comput Biol Med, 2012; 42 (3): 276-281.
  41. D. Kaloriti, A. Tillmann, E. Cook, M. Jacobsen, T. You, M. Lenardon, L. Ames, M. Barahona, K. Chandrasekaran, G. Coghill, D. Goodman, N.A. Gow, C. Grebogi, H.L. Ho, P. Ingram, A. McDonagh, A.P. Moura, W. Pang, M. Puttnam, E. Radmaneshfar, M.C. Romano, D. Silk, J. Stark, M. Stumpf, M. Thiel, T. Thorne, J. Usher, Z. Yin, K. Haynes, A.J. Brown: Combinatorial stresses kill pathogenic Candida species. Med Mycol, 2012;
  42. L. Sommerlade, M. Thiel, B. Platt, A. Plano, G. Riedel, C. Grebogi, J. Timmer, B. Schelter: Inference of Granger causal time-dependent influences in noisy multivariate time series. J Neurosci Methods, 2012; 203 (1): 173-185.
  43. M.S. Baptista, R.M. Rubinger, E.R. Viana, J.C. Sartorelli, U. Parlitz, C. Grebogi: Mutual information rate and bounds for it. Plos One, 2012; 7 (10): e46745.
  44. T. You, P. Ingram, M.D. Jacobsen, E. Cook, A. McDonagh, T. Thorne, M.D. Lenardon, A.P. de Moura, M.C. Romano, M. Thiel, M. Stumpf, N.A. Gow, K. Haynes, C. Grebogi, J. Stark, A.J. Brown: A systems biology analysis of long and short-term memories of osmotic stress adaptation in fungi. BMC Res Notes, 2012; 5 (1): 258.
  45. W.X. Wang, X. Ni, Y.C. Lai, C. Grebogi: Optimizing controllability of complex networks by minimum structural perturbations. Phys Rev E, 2012; 85 (2-2): 026115-026115.
  46. Y. Li, J. Wang, C. Grebogi, M. Foote, F. Liu: A syringe Focused Ultrasound Device for Simultaneous Injection of DNA and Gene Transfer. J Gene Med, 2012; 14 (1): 54-61.
  47. B. Spittau, K. Krieglstein: Klf10 and Klf11 as mediators of TGF-beta superfamily signaling. Cell and Tissue Research, 2012; 347 (1): 65-72.
  48. B. Spittau, L. Wullkopf, X. Zhou, J. Rilka, D. Pfeifer, K. Krieglstein: Endogenous transforming growth factor-beta promotes quiescence of primary microglia in vitro. Glia, 2012.
  49. B. Spittau, X. Zhou, M. Ming, K. Krieglstein: IL6 Protects MN9D Cells and Midbrain Dopaminergic Neurons from MPP(+)-Induced Neurodegeneration. Neuromol Med, 2012.
  50. X. Zhou, B. Spittau, K. Krieglstein: TGFbeta signalling plays an important role in IL4-induced alternative activation of microglia. J Neuroinflamm, 2012; 9 (1), 210.
  51. R. Ouchida H. Mori K. Hase H. Takatsu, T. Kurosaki, T. Tokuhisa H. Ohno J.Y. Wang: Critical role of the IgM Fc receptor in IgM homeostasis, B-cell survival, and humoral immune responses. P Natl Acad Sci Usa, 2012.
  52. T.D. Troutman, W. Hu, S. Fulenchek, T. Yamazaki, T. Kurosaki, J.F. Bazan, C. Pasare: Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt. P Natl Acad Sci Usa, 2012; 109 (1): 273-278.
  53. T. Onodera, Y. Takahashi, Y. Yokoi, M. Ato, Y. Kodama, S. Hachimura, T. Kurosaki, K. Kobayashi: Memory B cells in the lung participate in protective humoral immune responses to pulmonary influenza virus reinfection. P Natl Acad Sci Usa, 2012; 109 (7): 2485-2490.
  54. Y. Fujii, M. Shiota, Y. Ohkawa, A. Baba, H. Wanibuchi, T. Kinashi, T. Kurosaki, Y. Baba: Surf4 modulates STIM1-dependent calcium entry. Biochem Bioph Res Co, 2012.
  55. Y. Takahashi, T. Onodera, K. Kobayashi, T. Kurosaki: Primary and Secondary B-Cell Responses to Pulmonary Virus Infection. Infect Disord Drug Targets, 2012.
  56. E. Aichinger, N. Kornet, T. Friedrich, T. Laux: Plant Stem Cell Niches. Annual Review of Plant Biology, 2012; 63: 615-636.
  57. A. Joshi, Y. Beck, T. Michoel: Post-transcriptional regulatory networks play a key role in noise reduction which is conserved from micro-organisms to mammals. FEBS Journal, 2012;
  58. J. Qi, T. Michoel: Context-specific transcriptional regulatory network inference from global gene expression maps using double two-way t-tests. Bioinformatics, 2012; 28 (18): 2325-2332.
  59. J. Qi, T. Michoel, G. Butler: An Integrative Approach to Infer Regulation Programs in a Transcription Regulatory Module Network. Journal of Biomedicine and Biotechnology, 2012;
  60. M. Claeys, V. Storms, H. Sun, T. Michoel, K. Marchal: MotifSuite: workflow for probabilistic motif detection and assessment. Bioinformatics, 2012; 28 (14): 1931-1932.
  61. T. Michoel, B. Nachtergaele: Alignment and integration of complex networks by hypergraph-based spectral clustering. Physical Review E, 2012; 86 (5): 056111.
  62. B.H Cho, I. Cao-Berg, J.A. Bakal, R.F. Murphy: OMERO.searcher: content-based image search for microscope images. Nature Methods, 2012; 9 (7): 633-634.
  63. J. Li, L. Xiong, J. Schneider, R.F. Murphy: Protein subcellular location pattern classification in cellular images using latent discriminative models. Bioinformatics, 2012; 28 (12): i32-i39.
  64. R.F. Murphy: CellOrganizer: Image-Derived Models of Subcellular Organization and Protein Distribution. Method Cell Biol, 2012; 110: 179-193.
  65. R.F. Murphy, E. Komlodi-Pasztor, R. Robey, F.M. Balis, N.P. Farrell, T. Fojo: Retained platinum uptake and indifference to p53 status make novel transplatinum agents active in platinum-resistant cells compared to cisplatin and oxaliplatin. Cell Cycle, 2012; 11 (5).
  66. T. E. Buck, J. Li, G.K. Rohde, R.F. Murphy: Toward the virtual cell: Automated approaches to building models of subcellular organization "learned" from microscopy images. Bioessays, 2012; 34 (9): 791-799.
  67. A.E. Starr, A. Dufour, J. Maier, C.M. Overall: Biochemical analysis of matrix metalloproteinase activation of chemokines CCL15 and CCL23 and increased glycosaminoglycan binding of CCL16. J Biol Chem, 2012; 287 (8): 5948-5860.
  68. A.E. Starr, C.L. Bellac, A. Dufour, V. Goebeler, C.M. Overall: Biochemical characterization and N-terminomics analysis of leukolysin, the membrane-type 6 matrix metalloprotease (MMP25): chemokine and vimentin cleavages enhance cell migration and macrophase phagocytic activities. J Biol Chem, 2012; 287 (16): 13382-13395.
  69. C.D. Bosco, A. Dovzhenko, K. Palme: Intracellular auxin transport in pollen: PIN8, PIN5 and PILS5. Plant Signal Behav, 2012; 7 (11).
  70. C.D. Bosco, A. Dovzhenko, X. Liu, N. Woerner, T. Rensch, M. Eismann, S. Eimer, J. Hegermann, I.A. Paponov, B. Ruperti, E. Heberle-Bors, A. Touraev, J.D. Cohen, K. Palme: The endoplasmic reticulum localized PIN8 is a pollen specific auxin carrier involved in intracellular auxin homeostasis. Plant J , 2012.
  71. M.K. Singh, F. Ren, T. Giesemann, C.D. Bosco, T.P. Pasternak, T. Blein, B. Ruperti, G. Schmidt, K. Aktories, A.J. Molendijk, K. Palme: Modification of plant Rac/Rop GTPase signalling using bacterial toxin transgenes. Plant J, 2012.
  72. N.S. Kiran, E. Benkova, A. Rekova, J. Dubova, J. Malbeck, K. Palme, B. Brzobohaty: Retargeting a maize beta-glucosidase to the vacuole - Evidence from intact plants that zeatin-O-glucoside is stored in the vacuole. Phytochemistry , 2012; 69: 67-77.
  73. S. Trevisan, A. Nonis, M. Begheldo, A. Manoli, K. Palme, G. Caporale, B. Ruperti, S. Quaggiotti: Expression and tissue-specific localization of nitrate-responsive miRNAs in roots of maize seedlings. Plant Cell Environ, 2012; 35 (6): 1137-1155. (in Druck)
  74. A. Erxleben, A. Gessler, M. Vervliet-Scheebaum, R. Reski: Metabolite profiling of the moss Physcomitrella patens reveals evolutionary conservation of osmoprotective substances. Plant Cell Rep, 2012; 31 (2): 427-436.
  75. C. Kreutz, J.S. Gehring, D. Lang, R. ReskiJ. Timmer, S.A. Rensing: TSSi - An R package for transcription start site identification from 5’ mRNA tag data. Bioinformatics, 2012;
  76. E. L. Decker, R. Reski: Glycoprotein production in moss bioreactors. Plant Cell Reports, 2012; 31: 453-460.
  77. H. Birke, S.J. Müller, M. Rother, A.D. Zimmer, S.N.W. Hoernstein, D. Wesenberg, M. Wirtz, G.-J. Krauss, R. Reski, R. Hell: The relevance of compartmentation for cysteine synthesis in phototrophic organisms. Protoplasma, 2012; doi: 10.1007/s00709-012-0411-9.
  78. J. Harba, O. Salehb, D. Kittemann, D.A. Neuwald, W. Frankd, R. Reski: Upregulation of polyphenol-related genes prevents ‘skin burning’ of well-colored ‘Cameo’ apples stored under stressful controlled atmosphere conditions. Postharvest Biol Tec, 2012: 1-7.
  79. J. Parsons, F. Altmann, C.K. Arrenberg, A. Koprivova, A.K. Beike, C. Stemmer, G. Gorr, R. Reski, E.L. Decker: Moss-based production of asialo-erythropoietin devoid of Lewis A and other plant-typical carbohydrate determinants. Plant Biotechnol J, 2012.
  80. J. Scholz, F. Brodhun, E. Hornung, C. Herrfurth, M. Stumpe, A.K. Beike, B. Faltin, W. Frank, R. Reski, I. Feussner: Biosynthesis of allene oxides in Physcomitrella patens. Bmc Plant Biol, 2012; 12 (1): 228.
  81. M.A. Arif, I. Fattash, Z. Ma, S.H. Cho, A.K. Beike, R. Reski, M.J. Axtell, W. Frank: DICER-LIKE3 Activity in Physcomitrella patens DICER-LIKE4 Mutants Causes Severe Developmental Dysfunction and Sterility. Mol Plant, 2012; 5 (6): 1281-1294.
  82. M. T. Lehtonen, M. Akita, W. Frank, R. Reski, J.P.T. Valkonen: Involvement of a class III peroxidase and the mitochondrial protein TSPO in oxidative burst upon treatment of moss plants with a fungal elicitor. Molecular Plant-Microbe Interactions, 2012; 25: 363-371.
  83. S.Y. Kim, C.C. Colpitts, G. Wiedemann, C. Jepson, M. Rahimi, J.R. Rothwell, A.D. McInnes, T. Tanahashi, M. Hasebe, R. Reski, B.T. Sterenberg, D.-Y. Suh: Physcomitrella PpORS, basal to plant type III polyketide synthases in phylogenetic trees, is a very long chain 2’-oxoalkylresorcinol synthase. Journal of Biological Chemistry, 2012;
  84. A. Rodriguez, M. Schelker, M. Schilling, J. Bachmann, A. Raue, F. Salopiata, S. Depner, L. Adlung, R. Merkle, A. Franke, M. Jarsch, J. Timmer, U. Klingmueller: Epo and EpoR signaling dynamic in hematopoietic and tumor context. American Journal of Hematology, 2012; 87 (10): E116
  85. A. Yalcin, C. Kreutz, D. Pfeifer, M. Abdelkarim, G. Klaus, J. Timmer, M. Lubbert, B. Hackanson: MeDIP coupled with a promoter tiling array as a platform to investigate global DNA methylation patterns in AML cells. Leukemia Res, 2012.
  86. B. Greese, K. Wester, R. Bensch, O. Ronneberger, J. Timmer, M. Huelskamp, C. Fleck: Influence of cell-to-cell variability on spatial pattern formation. IET Systems Biology, 2012; 6 (4): 143-153.
  87. B. Steiert, A. Raue, J. Timmer, C. Kreutz: Experimental design for parameter estimation of gene regulatory networks. Plos One, 2012; 7(7): e40052-e40052.
  88. C. Kreutz, A. Raue, J. Timmer: Likelihood based observability analysis and confidence intervals for predictions of dynamic models. Bmc Syst Biol, 2012; 6(1): 120.
  89. D. Kaschek, J. Timmer: A variational approach to parameter estimation in ordinary differential equations. Bmc Syst Biol, 2012; 6(1): 99.
  90. J. Bachmann, A. Raue, M. Schilling, V. Becker, J. Timmer, U. Klingmuller: Predictive Mathematical Models of Cancer Signalling Pathways. J Intern Med, 2012; 271 (2): 155-165.
  91. J. Klatt, H. Feldwisch-Drentrup, M. Ihle, V. Navarro, M. Neufang, C. Teixeira, C. Adam, M. Valderrama, C. Alvarado-Rojas, A. Witon, M. Le Van Quyen, F. Sales, A. Dourado, J. Timmer, A. Schulze-Bonhage, B. Schelter: The EPILEPSIAE database: An extensive electroencephalography database of epilepsy patients. Epilepsia, 2012; 53 (9): 1669-1676.
  92. K.S. Ferreira, C. Kreutz, S. Macnelly, K. Neubert, A. Haber, M. Bogyo, J. Timmer, C. Borner: Caspase-3 feeds back on caspase-8, Bid and XIAP in type I Fas signaling in primary mouse hepatocytes. Apoptosis, 2012; 17 (5): 503-515.
  93. L. Sommerlade, B. Schelter, J. Timmer, M. Reinhard: Grading of Dynamic Cerebral Autoregulation Without Blood Pressure Recordings: A Simple Doppler-based Method. Ultrasound Med Biol , 2012.
  94. M. Ihle, H. Feldwisch-Dentrup, C.A. Teixeira, A. Witon, B. Schelter, J. Timmer, A. Schulze-Bonhage: EPILEPSIAE - A European epilepsy database. Computer Methods and Programs in Biomedicine, 2012; 106 (3): 127-138.
  95. M.M. Kampf, R. Engesser, M. Busacker, M. Horner, M. Karlsson, M.D. Zurbriggen, M. Fussenegger, J. Timmer, W. Weber: Rewiring and dosing of systems modules as a design approach for synthetic mammalian signaling networks. Mol Biosyst, 2012; 8 (6): 1824-1832.
  96. M. Schelker, A. Raue, J. Timmer, C. Kreutz: Comprehensive estimation of input signals and dynamics in biochemical reaction networks. Bioinformatics, 2012; 28 (18): I529-I534.
  97. R. Schlatter, N. Philippi, G. Wangorsch, R. Pick, O. Sawodny, C. Borner, J. Timmer, M. Ederer, T. Dandekar: Integration of Boolean models exemplified on hepatocyte signal transduction. Briefings in Bioinformatics, 2012; 13 (3): 365-376.
  98. T. Maiwald, J. Blumberg, A. Raue, S. Hengl, M. Schilling, S.K. Sy, V. Becker, U. Klingmuller, J. Timmer: In silico labeling reveals the time-dependent label half-life and transit-time in dynamical systems. Bmc Syst Biol, 2012; 6 (1): 13.
  99. V. Becker, J. Timmer, U. Klingmuller: Receptor dynamics in signaling. Adv Exp Med Biol, 2012; 736: 313-323.
  100. D. Fuchs-Telem, O. Sarig, M.A. van Steensel, O. Isakov, S. Israeli, J. Nousbeck, K. Richard, V. Winnepenninckx, M. Vernooij, N. Shomron, J. Uitto, P. Fleckman, G. Richard, E. Sprecher: Familial Pityriasis Rubra Pilaris Is Caused by Mutations in CARD14. Am J Hum Genet, 2012.
  101. E.A. Kupetsky-Rincon, Q. Li, J. Uitto: Magnesium reduces carotid intima-media thickness in a mouse model of pseudoxanthoma elasticum: a novel treatment biomarker. Clin Transl Sci, 2012; 5 (3): 259-264.
  102. E.A. Kupetsky-Rincon, J. Uitto: Magnesium: Novel Applications in Cardiovascular Disease - A Review of the Literature.Ann Nutr Metab, 2012; 61 (2): 102-110.
  103. J.C. Salas-Alanis, R. Cepeda-Valdes, J.E. Mellerio, A.M. Christiano, J. Uitto: Progress in epidermolysis bullosa: summary of a workshop in CILAD-2010*Int J Dermatol, 2012; 51 (6): 682-687.
  104. J. Uitto, C. Has, L. Bruckner-Tuderman: Cell-based therapies for epidermolysis bullosa - from bench to bedside.J Dtsch Dermatol Ges, 2012; 10 (11): 803-807.
  105. J. Uitto, U. Rodeck: Integration of investigative dermatology into the global biomedical research enterprise: past, present, and future. J Invest Dermatol, 2012; 132 (3 Pt 2): 1029-1032.
  106. J. Uitto, A.M. Christiano, W.H. McLean, J.A. McGrath: Novel Molecular Therapies for Heritable Skin Disorders. J Invest Dermatol, 2012; 132 (3 Pt 2): 820-828.
  107. J. Uitto: Rare heritable skin diseases: targets for regenerative medicine. J Invest Dermatol, 2012; 132 (11): 2485-2488.
  108. J. Uitto, Q. Li, Z. Urban: The complexity of elastic fibre biogenesis in the skin - a perspective to the clinical heterogeneity of cutis laxa. Exp Dermatol, 2012.
  109. M. El-Domyati, T.S. El-Ammawi, W. Medhat, O. Moawad, M.G. Mahoney, J. Uitto: Multiple minimally invasive Erbium: Yttrium Aluminum Garnet laser mini-peels for skin rejuvenation: an objective assessment. J Cosmet Dermatol, 2012; 11 (2): 122-130.
  110. N.B. Kavukcuoglu, Q. Li, N. Pleshko,  J. Uitto: Connective tissue mineralization in Abcc6(-/-) mice, a model for pseudoxanthoma elasticum., Matrix Biol, 2012; 31 (4): 246-252.
  111. Q. Jiang, J. Uitto: Restricting dietary magnesium accelerates ectopic connective tissue mineralization in a mouse model of pseudoxanthoma elasticum (Abcc6(-/-) ).Exp Dermatol, 2012; 21 (9): 694-699.
  112. Q. Li, H. Guo, H. Matsui, H. Honda, T. Inaba, J.P. Sundberg, E. Sprecher, J. Uitto: Mouse Samd9l is not a functional paralogue of the human SAMD9, the gene mutated in normophosphataemic familial tumoral calcinosis.Exp Dermatol, 2012; 21 (7): 554-556.
  113. H. Tsuboi, S. Nakamura, E. Schaefer, M. Wada: Red Light-Induced Phytochrome Relocation into the Nucleus in Adiantum capillus-veneris. MOLECULAR PLANT, 2012; 5 (3): 611-618.