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Sie sind hier: FRIAS School of Life Sciences … Fellows Bente Finsen

Bente Finsen

External Senior Fellow
November 2011 - October 2012

Tel. +45 6550 3990
Fax +45 6550 3950

    CV

    Bente Finsen, born in Viborg on March 17th, 1961, studied Medicine at the Aarhus University in Denmark where she received her MD in 1988. After a short excursion to industry at PharmaBiotec, Danish State Biotechnology Programe she graduated as PhD in the field of Neurobiology at the Faculty of Health Sciences, Aarhus University, already also being associate professor at the Department of Anatomy and Cell Biology at Odense University. From 1998-1999 Bente Finsen was a visiting scientist at the Laboratory of Developmental Biology in the Molecular Oncology Group at McGill University in Montreal, Canada. In 2000 Professor Finsen returned to Denmark to become a full professor at the Department of Anatomy and Neurobiology, Institute of Medical Biology, University of Southern Denmark (Odense Campus). Since 2004 Bente Finsen holds a professorship at the Medical Biotechnology Center, Institute of Medical Biology, at the University of Southern Denmark (Odense Campus). During the last 20 years Professor Finsen earned quite some awards, under which the Danish Alzheimer Society Research Foundation Award in 2006. She is member of several Research Societies like the European Society for Neuroscience, the Society for Neuroscience and International Society for Neuroimmunology. From 2002-2008 she was a Board member of the Danish Medical Research Council (MRC).

     

    FRIAS Project

    Lesion-Directed Expression of Chemotactic Molecules in Cortical Neurons

    Research fields

    - Innate microglial responses to acute brain injury

    - Molecular and cellular mechanisms of remyelination

    - Neuroinflammation in Alzheimer´s and Alzheimer´s-like disease

     

    Selected Publications

    1. K.L. Lambertsen, K. Biber, B. Finsen: Inflammatory cytokines in experimental and human stroke. J Cerebr Blood F Met, 2012; 32 (9): 1677-1698. http://dx.doi.org/10.1038/jcbfm.2012.88
    2. D. Neess, M. Bloksgaard, S. Bek, B. Finsen, S. Mandrup: Disruption of the Acyl-CoA-binding Protein Gene Delays Hepatic Adaptation to Metabolic Changes at Weaning J Biol Chem, 2011; 286 (5): 3460-3472
    3. K.L. Lambertsen, T. Deierborg, R. Gregersen, H.H. Nielsen, F.F. Johansen, F. Flemming, B. Finsen: Differences in Origin of Reactive Microglia in Bone Marrow Chimeric Mouse and Rat After Transient Global Ischemia Journal of Neuropathology and Experimental Neurology, 2011; 70 (6): 481-494
    4. N. Drojdahl, N.H. Nielsen, J.E. Gardi, A. Wree, A.C. Peterson, J.R. Nyengaard, J. Eyer, B. Finsen: Axonal Plasticity Elicits Long-Term Changes in Oligodendroglia and Myelinated Fibers Glia, 2010; 58 (1): 29-42
    5. S.D. Santos, K.L. Lambertsen, B.H. Clausen, A. Akinc, R. Alvarez, B. Finsen, M.J. Saraiva: CSF transthyretin neuroprotection in a mouse model of brain ischemia. Journal of Neurochemistry, 2010; 115 (6): 1434-1444
    6. KL. Lambertsen, BH. Clausen, A. Babcock, R. Gregersen, C. Fenger, HH. Nielsen, LS. Haugaard, M. Wirenfeldt, M. Nielsen, F. Dagnæs-Hansen, H. Bluethmann, NJ. Færgeman, M. Meldgaard, T. Deierborg, B. Finsen (2009) Microglia protect neurons against ischemia by synthesis of tumor necrosis factor, Neurosci. 29: 1319-1330
    7. HH. Nielsen, R. Ladeby, C. Fenger, H. Toft-Hansen, AA. Babcock, T. Owens, B. Finsen (2009) Enhanced microglial clearance of myelin debris in T cell infiltrated central nervous systems, J. Neuropathol Exp Neurol. 68: 845-56
    8. L. Lyck, I. Dalmau Santamaria, B. Pakkenberg, J. Chemnitz, HD. Schrøder, B. Finsen, HJG. Gundersen (2009) An empirical analysis of the precision of estimating the numbers of neurons and glia in human neocortex using a fractionator-design with sub-sampling, J. Neurosci Meth. 182: 143-56
    9. BH. Clausen, KL. Lambertsen, AA. Babcock, T. Holm, F. Dagnæs-Hansen, B. Finsen (2008) Interleukin - 1ß and tumor necrosis factor-a are expressed by different subsets of microglia and macrophages after ischemic stroke in mice. J. Neuroinflam. 5:46
    10. M. Wirenfeldt, L. Dissing-Olesen, AA. Babcock, M. Nielsen, M. Melgaard, J. Zimmer, I. Azcoitia, RGQ. Leslie, F. Dagnæs-Hansen, B. Finsen (2007) Population control of resident and immigrating microglia by mitosis and apoptosis, Am J Pathol 171: 17-31